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Altering distribution profile of palbociclib by its prodrugs.
Järvinen J, Montaser AB, Adla SK, Leppänen J, Lehtonen M, Vellonen KS, Laitinen T, Jalkanen A, Elmquist WF, Timonen J, Huttunen KM, Rautio J. Järvinen J, et al. Among authors: lehtonen m. Eur J Pharm Sci. 2024 Jan 1;192:106637. doi: 10.1016/j.ejps.2023.106637. Epub 2023 Nov 13. Eur J Pharm Sci. 2024. PMID: 37967656 Free article.
How readily does ketorolac penetrate cerebrospinal fluid in children?
Kumpulainen E, Kokki H, Laisalmi M, Heikkinen M, Savolainen J, Rautio J, Lehtonen M. Kumpulainen E, et al. Among authors: lehtonen m. J Clin Pharmacol. 2008 Apr;48(4):495-501. doi: 10.1177/0091270007313389. Epub 2008 Feb 13. J Clin Pharmacol. 2008. PMID: 18272673 Clinical Trial.
Diclofenac readily penetrates the cerebrospinal fluid in children.
Kokki H, Kumpulainen E, Laisalmi M, Savolainen J, Rautio J, Lehtonen M. Kokki H, et al. Among authors: lehtonen m. Br J Clin Pharmacol. 2008 Jun;65(6):879-84. doi: 10.1111/j.1365-2125.2008.03126.x. Br J Clin Pharmacol. 2008. PMID: 18477264 Free PMC article.
Brain uptake of ketoprofen-lysine prodrug in rats.
Gynther M, Jalkanen A, Lehtonen M, Forsberg M, Laine K, Ropponen J, Leppänen J, Knuuti J, Rautio J. Gynther M, et al. Among authors: lehtonen m. Int J Pharm. 2010 Oct 31;399(1-2):121-8. doi: 10.1016/j.ijpharm.2010.08.019. Epub 2010 Aug 19. Int J Pharm. 2010. PMID: 20727958
Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase.
Aaltonen N, Savinainen JR, Ribas CR, Rönkkö J, Kuusisto A, Korhonen J, Navia-Paldanius D, Häyrinen J, Takabe P, Käsnänen H, Pantsar T, Laitinen T, Lehtonen M, Pasonen-Seppänen S, Poso A, Nevalainen T, Laitinen JT. Aaltonen N, et al. Among authors: lehtonen m. Chem Biol. 2013 Mar 21;20(3):379-90. doi: 10.1016/j.chembiol.2013.01.012. Chem Biol. 2013. PMID: 23521796
269 results