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Anti-CD38 antibody therapy for patients with relapsed/refractory multiple myeloma: differential mechanisms of action and recent clinical trial outcomes.
Leleu X, Martin T, Weisel K, Schjesvold F, Iida S, Malavasi F, Manier S, Chang-Ki Min, Ocio EM, Pawlyn C, Perrot A, Quach H, Richter J, Spicka I, Yong K, Richardson PG. Leleu X, et al. Ann Hematol. 2022 Oct;101(10):2123-2137. doi: 10.1007/s00277-022-04917-5. Epub 2022 Aug 9. Ann Hematol. 2022. PMID: 35943588 Free PMC article. Review.
Emerging drugs in multiple myeloma.
Ghobrial IM, Leleu X, Hatjiharissi E, Hideshima T, Mitsiades C, Schlossman R, Anderson KC, Richardson P. Ghobrial IM, et al. Among authors: leleu x. Expert Opin Emerg Drugs. 2007 Mar;12(1):155-63. doi: 10.1517/14728214.12.1.155. Expert Opin Emerg Drugs. 2007. PMID: 17355220 Review.
Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma.
Younes H, Leleu X, Hatjiharissi E, Moreau AS, Hideshima T, Richardson P, Anderson KC, Ghobrial IM. Younes H, et al. Among authors: leleu x. Clin Cancer Res. 2007 Jul 1;13(13):3771-5. doi: 10.1158/1078-0432.CCR-06-2921. Clin Cancer Res. 2007. PMID: 17606706 Review.
Novel therapeutic avenues in myeloma: changing the treatment paradigm.
Ghobrial J, Ghobrial IM, Mitsiades C, Leleu X, Hatjiharissi E, Moreau AS, Roccaro A, Schlossman R, Hideshima T, Anderson KC, Richardson P. Ghobrial J, et al. Among authors: leleu x. Oncology (Williston Park). 2007 Jun;21(7):785-92; discussion 798-800. Oncology (Williston Park). 2007. PMID: 17722741 Review.
Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment.
Huston A, Leleu X, Jia X, Moreau AS, Ngo HT, Runnels J, Anderson J, Alsayed Y, Roccaro A, Vallet S, Hatjiharissi E, Tai YT, Sportelli P, Munshi N, Richardson P, Hideshima T, Roodman DG, Anderson KC, Ghobrial IM. Huston A, et al. Among authors: leleu x. Clin Cancer Res. 2008 Feb 1;14(3):865-74. doi: 10.1158/1078-0432.CCR-07-1299. Clin Cancer Res. 2008. PMID: 18245550
International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation.
Palumbo A, Sezer O, Kyle R, Miguel JS, Orlowski RZ, Moreau P, Niesvizky R, Morgan G, Comenzo R, Sonneveld P, Kumar S, Hajek R, Giralt S, Bringhen S, Anderson KC, Richardson PG, Cavo M, Davies F, Bladé J, Einsele H, Dimopoulos MA, Spencer A, Dispenzieri A, Reiman T, Shimizu K, Lee JH, Attal M, Boccadoro M, Mateos M, Chen W, Ludwig H, Joshua D, Chim J, Hungria V, Turesson I, Durie BG, Lonial S; IMWG. Palumbo A, et al. Leukemia. 2009 Oct;23(10):1716-30. doi: 10.1038/leu.2009.122. Epub 2009 Jun 4. Leukemia. 2009. PMID: 19494840 Review.
Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia.
Ghobrial IM, Roccaro A, Hong F, Weller E, Rubin N, Leduc R, Rourke M, Chuma S, Sacco A, Jia X, Azab F, Azab AK, Rodig S, Warren D, Harris B, Varticovski L, Sportelli P, Leleu X, Anderson KC, Richardson PG. Ghobrial IM, et al. Among authors: leleu x. Clin Cancer Res. 2010 Feb 1;16(3):1033-41. doi: 10.1158/1078-0432.CCR-09-1837. Epub 2010 Jan 26. Clin Cancer Res. 2010. PMID: 20103671 Free PMC article. Clinical Trial.
Prognostic value of PINI index in patients with multiple myeloma.
Dupire S, Wemeau M, Debarri H, Pascal L, Hivert B, Willekens C, Boyle E, Manier S, Béatrice T, Onraed B, Faucompré JL, Hennache B, Dumontet C, Facon T, Leleu X. Dupire S, et al. Among authors: leleu x. Eur J Haematol. 2012 Apr;88(4):306-13. doi: 10.1111/j.1600-0609.2011.01740.x. Epub 2012 Jan 4. Eur J Haematol. 2012. PMID: 22126676
Bone marrow microenvironment in multiple myeloma progression.
Manier S, Sacco A, Leleu X, Ghobrial IM, Roccaro AM. Manier S, et al. Among authors: leleu x. J Biomed Biotechnol. 2012;2012:157496. doi: 10.1155/2012/157496. Epub 2012 Oct 3. J Biomed Biotechnol. 2012. PMID: 23093834 Free PMC article. Review.
378 results