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Page 1
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis.
Venkateswaran N, Garcia R, Lafita-Navarro MC, Hao YH, Perez-Castro L, Nogueira PAS, Solmonson A, Mender I, Kilgore JA, Fang S, Brown IN, Li L, Parks E, Lopes Dos Santos I, Bhaskar M, Kim J, Jia Y, Lemoff A, Grishin NV, Kinch L, Xu L, Williams NS, Shay JW, DeBerardinis RJ, Zhu H, Conacci-Sorrell M. Venkateswaran N, et al. Among authors: lemoff a. Nat Commun. 2024 May 20;15(1):4266. doi: 10.1038/s41467-024-47868-3. Nat Commun. 2024. PMID: 38769298
PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer.
Lin CC, Chang TC, Wang Y, Guo L, Gao Y, Bikorimana E, Lemoff A, Fang YV, Zhang H, Zhang Y, Ye D, Soria-Bretones I, Servetto A, Lee KM, Luo X, Otto JJ, Akamatsu H, Napolitano F, Mani R, Cescon DW, Xu L, Xie Y, Mendell JT, Hanker AB, Arteaga CL. Lin CC, et al. Among authors: lemoff a. Nat Commun. 2024 Mar 13;15(1):2287. doi: 10.1038/s41467-024-46495-2. Nat Commun. 2024. PMID: 38480701 Free PMC article.
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L. Nguyen BA, et al. Among authors: lemoff a. Nat Commun. 2024 Jan 17;15(1):581. doi: 10.1038/s41467-024-44820-3. Nat Commun. 2024. PMID: 38233397 Free PMC article.
UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance.
Rodriguez Tirado C, Wang C, Li X, Deng S, Gonzalez J, Johnson NA, Xu Y, Metang LA, Sundar Rajan M, Yang Y, Yin Y, Hofstad M, Raj GV, Zhang S, Lemoff A, He W, Fan J, Wang Y, Wang T, Mu P. Rodriguez Tirado C, et al. Among authors: lemoff a. Oncogene. 2024 Jan;43(4):265-280. doi: 10.1038/s41388-023-02890-5. Epub 2023 Nov 29. Oncogene. 2024. PMID: 38030789 Free PMC article.
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.
Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, David HE, Torres TP, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Folta-Stogniew E, Yang ZJ, Skaar EP, Byndloss MX, Chazin WJ, Zhu W. Spiga L, et al. Among authors: lemoff a. Cell Host Microbe. 2023 Oct 11;31(10):1639-1654.e10. doi: 10.1016/j.chom.2023.08.018. Epub 2023 Sep 29. Cell Host Microbe. 2023. PMID: 37776864
VCP increases or decreases tau seeding using specific cofactors.
Batra S, Vaquer-Alicea J 3rd, Manon VA, Kashmer OM, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: lemoff a. bioRxiv [Preprint]. 2023 Aug 30:2023.08.30.555637. doi: 10.1101/2023.08.30.555637. bioRxiv. 2023. PMID: 37693404 Free PMC article. Preprint.
Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle.
Sacharidou A, Chambliss K, Peng J, Barrera J, Tanigaki K, Luby-Phelps K, Özdemir İ, Khan S, Sirsi SR, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Kanchwala M, Sathe AA, Lemoff A, Xing C, Hoyt K, Mineo C, Shaul PW. Sacharidou A, et al. Among authors: lemoff a. Nat Commun. 2023 Aug 17;14(1):4989. doi: 10.1038/s41467-023-40562-w. Nat Commun. 2023. PMID: 37591837 Free PMC article.
51 results