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Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4.
Montecucco F, Braunersreuther V, Burger F, Lenglet S, Pelli G, Carbone F, Fraga-Silva R, Stergiopulos N, Monaco C, Mueller C, Pagano S, Dallegri F, Mach F, Vuilleumier N. Montecucco F, et al. Among authors: lenglet s. Thromb Haemost. 2015 Aug;114(2):410-22. doi: 10.1160/TH14-12-1039. Epub 2015 Apr 16. Thromb Haemost. 2015. PMID: 25879306
The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.
Montecucco F, Di Marzo V, da Silva RF, Vuilleumier N, Capettini L, Lenglet S, Pagano S, Piscitelli F, Quintao S, Bertolotto M, Pelli G, Galan K, Pilet L, Kuzmanovic K, Burger F, Pane B, Spinella G, Braunersreuther V, Gayet-Ageron A, Pende A, Viviani GL, Palombo D, Dallegri F, Roux-Lombard P, Santos RA, Stergiopulos N, Steffens S, Mach F. Montecucco F, et al. Among authors: lenglet s. Eur Heart J. 2012 Apr;33(7):846-56. doi: 10.1093/eurheartj/ehr449. Epub 2011 Nov 22. Eur Heart J. 2012. PMID: 22112961 Free PMC article.
Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability.
Quercioli A, Mach F, Bertolotto M, Lenglet S, Vuilleumier N, Galan K, Pagano S, Braunersreuther V, Pelli G, Pistoia V, Bianchi G, Cittadini G, Viviani GL, Pende A, Roux-Lombard P, Thomas A, Staub C, Ratib O, Dallegri F, Schindler TH, Montecucco F. Quercioli A, et al. Among authors: lenglet s. Thromb Haemost. 2012 Jan;107(1):124-39. doi: 10.1160/TH11-05-0324. Epub 2011 Nov 24. Thromb Haemost. 2012. PMID: 22116393
Role of matrix metalloproteinase-8 in atherosclerosis.
Lenglet S, Mach F, Montecucco F. Lenglet S, et al. Mediators Inflamm. 2013;2013:659282. doi: 10.1155/2013/659282. Epub 2013 Jan 9. Mediators Inflamm. 2013. PMID: 23365489 Free PMC article. Review.
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice.
Nencioni A, da Silva RF, Fraga-Silva RA, Steffens S, Fabre M, Bauer I, Caffa I, Magnone M, Sociali G, Quercioli A, Pelli G, Lenglet S, Galan K, Burger F, Vázquez Calvo S, Bertolotto M, Bruzzone S, Ballestrero A, Patrone F, Dallegri F, Santos RA, Stergiopulos N, Mach F, Vuilleumier N, Montecucco F. Nencioni A, et al. Among authors: lenglet s. Thromb Haemost. 2014 Feb;111(2):308-22. doi: 10.1160/TH13-07-0531. Epub 2013 Nov 7. Thromb Haemost. 2014. PMID: 24196571 Free article.
Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.
Lenglet S, Quercioli A, Fabre M, Galan K, Pelli G, Nencioni A, Bauer I, Pende A, Python M, Bertolotto M, Spinella G, Pane B, Palombo D, Dallegri F, Mach F, Vuilleumier N, Montecucco F. Lenglet S, et al. Mediators Inflamm. 2014;2014:720987. doi: 10.1155/2014/720987. Epub 2014 Feb 6. Mediators Inflamm. 2014. PMID: 24648660 Free PMC article.
Treatment with sulphated galactan inhibits macrophage chemotaxis and reduces intraplaque macrophage content in atherosclerotic mice.
Gomes Quinderé AL, Barros Benevides NM, Pelli G, Lenglet S, Burger F, Carbone F, Fraga-Silva RA, Stergiopulos N, Pagano S, Bertolotto M, Dallegri F, Vuilleumier N, Mach F, Montecucco F. Gomes Quinderé AL, et al. Among authors: lenglet s. Vascul Pharmacol. 2015 Aug;71:84-92. doi: 10.1016/j.vph.2015.02.015. Epub 2015 Apr 10. Vascul Pharmacol. 2015. PMID: 25869506
79 results