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Page 1
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.
Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, Ridker PM, Milligan PE, Grice G, Lenzini P, Rettie AE, Aquilante CL, Grosso L, Marsh S, Langaee T, Farnett LE, Voora D, Veenstra DL, Glynn RJ, Barrett A, McLeod HL. Gage BF, et al. Among authors: lenzini p. Clin Pharmacol Ther. 2008 Sep;84(3):326-31. doi: 10.1038/clpt.2008.10. Epub 2008 Feb 27. Clin Pharmacol Ther. 2008. PMID: 18305455 Free PMC article.
Gamma-glutamyl carboxylase and its influence on warfarin dose.
King CR, Deych E, Milligan P, Eby C, Lenzini P, Grice G, Porche-Sorbet RM, Ridker PM, Gage BF. King CR, et al. Among authors: lenzini p. Thromb Haemost. 2010 Oct;104(4):750-4. doi: 10.1160/TH09-11-0763. Epub 2010 Aug 5. Thromb Haemost. 2010. PMID: 20694283 Free PMC article.
Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles.
Lindley KJ, Limdi NA, Cavallari LH, Perera MA, Lenzini P, Johnson JA, Wu AHB, Ridker PM, King CR, Eby CS, Patel S, Shah SV, Beasley TM, Li J, Gage BF. Lindley KJ, et al. Among authors: lenzini p. Clin Pharmacol Ther. 2022 Apr;111(4):950-955. doi: 10.1002/cpt.2549. Epub 2022 Feb 27. Clin Pharmacol Ther. 2022. PMID: 35108398
Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedic patients.
Lenzini PA, Grice GR, Milligan PE, Dowd MB, Subherwal S, Deych E, Eby CS, King CR, Porche-Sorbet RM, Murphy CV, Marchand R, Millican EA, Barrack RL, Clohisy JC, Kronquist K, Gatchel SK, Gage BF. Lenzini PA, et al. J Thromb Haemost. 2008 Oct;6(10):1655-62. doi: 10.1111/j.1538-7836.2008.03095.x. Epub 2008 Jul 24. J Thromb Haemost. 2008. PMID: 18662264 Free PMC article.
A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans.
Voora D, Koboldt DC, King CR, Lenzini PA, Eby CS, Porche-Sorbet R, Deych E, Crankshaw M, Milligan PE, McLeod HL, Patel SR, Cavallari LH, Ridker PM, Grice GR, Miller RD, Gage BF. Voora D, et al. Among authors: lenzini pa. Clin Pharmacol Ther. 2010 Apr;87(4):445-51. doi: 10.1038/clpt.2009.291. Epub 2010 Mar 3. Clin Pharmacol Ther. 2010. PMID: 20200517 Free PMC article.
Integration of genetic, clinical, and INR data to refine warfarin dosing.
Lenzini P, Wadelius M, Kimmel S, Anderson JL, Jorgensen AL, Pirmohamed M, Caldwell MD, Limdi N, Burmester JK, Dowd MB, Angchaisuksiri P, Bass AR, Chen J, Eriksson N, Rane A, Lindh JD, Carlquist JF, Horne BD, Grice G, Milligan PE, Eby C, Shin J, Kim H, Kurnik D, Stein CM, McMillin G, Pendleton RC, Berg RL, Deloukas P, Gage BF. Lenzini P, et al. Clin Pharmacol Ther. 2010 May;87(5):572-8. doi: 10.1038/clpt.2010.13. Epub 2010 Apr 7. Clin Pharmacol Ther. 2010. PMID: 20375999 Free PMC article.
Genetic-based dosing in orthopedic patients beginning warfarin therapy.
Millican EA, Lenzini PA, Milligan PE, Grosso L, Eby C, Deych E, Grice G, Clohisy JC, Barrack RL, Burnett RS, Voora D, Gatchel S, Tiemeier A, Gage BF. Millican EA, et al. Blood. 2007 Sep 1;110(5):1511-5. doi: 10.1182/blood-2007-01-069609. Epub 2007 Mar 26. Blood. 2007. PMID: 17387222 Free PMC article. Clinical Trial.
Optimal initial dose adjustment of warfarin in orthopedic patients.
Lenzini PA, Grice GR, Milligan PE, Gatchel SK, Deych E, Eby CS, Burnett RS, Clohisy JC, Barrack RL, Gage BF. Lenzini PA, et al. Ann Pharmacother. 2007 Nov;41(11):1798-804. doi: 10.1345/aph.1K197. Epub 2007 Oct 2. Ann Pharmacother. 2007. PMID: 17911206
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.
Limdi NA, Wadelius M, Cavallari L, Eriksson N, Crawford DC, Lee MT, Chen CH, Motsinger-Reif A, Sagreiya H, Liu N, Wu AH, Gage BF, Jorgensen A, Pirmohamed M, Shin JG, Suarez-Kurtz G, Kimmel SE, Johnson JA, Klein TE, Wagner MJ; International Warfarin Pharmacogenetics Consortium. Limdi NA, et al. Blood. 2010 May 6;115(18):3827-34. doi: 10.1182/blood-2009-12-255992. Epub 2010 Mar 4. Blood. 2010. PMID: 20203262 Free PMC article.
Estimation of the warfarin dose with clinical and pharmacogenetic data.
International Warfarin Pharmacogenetics Consortium; Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MT, Limdi NA, Page D, Roden DM, Wagner MJ, Caldwell MD, Johnson JA. International Warfarin Pharmacogenetics Consortium, et al. N Engl J Med. 2009 Feb 19;360(8):753-64. doi: 10.1056/NEJMoa0809329. N Engl J Med. 2009. PMID: 19228618 Free PMC article.
32 results