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Diets rich in whole grains increase betainized compounds associated with glucose metabolism.
Kärkkäinen O, Lankinen MA, Vitale M, Jokkala J, Leppänen J, Koistinen V, Lehtonen M, Giacco R, Rosa-Sibakov N, Micard V, Rivellese AAA, Schwab U, Mykkänen H, Uusitupa M, Kolehmainen M, Riccardi G, Poutanen K, Auriola S, Hanhineva K. Kärkkäinen O, et al. Among authors: leppanen j. Am J Clin Nutr. 2018 Nov 1;108(5):971-979. doi: 10.1093/ajcn/nqy169. Am J Clin Nutr. 2018. PMID: 30256894 Free article. Clinical Trial.
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET).
Tuomainen M, Kärkkäinen O, Leppänen J, Auriola S, Lehtonen M, Savolainen MJ, Hermansen K, Risérus U, Åkesson B, Thorsdottir I, Kolehmainen M, Uusitupa M, Poutanen K, Schwab U, Hanhineva K. Tuomainen M, et al. Among authors: leppanen j. Am J Clin Nutr. 2019 Nov 1;110(5):1108-1118. doi: 10.1093/ajcn/nqz179. Am J Clin Nutr. 2019. PMID: 31504116 Free article. Clinical Trial.
Brain uptake of ketoprofen-lysine prodrug in rats.
Gynther M, Jalkanen A, Lehtonen M, Forsberg M, Laine K, Ropponen J, Leppänen J, Knuuti J, Rautio J. Gynther M, et al. Among authors: leppanen j. Int J Pharm. 2010 Oct 31;399(1-2):121-8. doi: 10.1016/j.ijpharm.2010.08.019. Epub 2010 Aug 19. Int J Pharm. 2010. PMID: 20727958
Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase.
Lukin A, Kramer J, Hartmann M, Weizel L, Hernandez-Olmos V, Falahati K, Burghardt I, Kalinchenkova N, Bagnyukova D, Zhurilo N, Rautio J, Forsberg M, Ihalainen J, Auriola S, Leppänen J, Konstantinov I, Pogoryelov D, Proschak E, Dar'in D, Krasavin M. Lukin A, et al. Among authors: leppanen j. Bioorg Chem. 2018 Oct;80:655-667. doi: 10.1016/j.bioorg.2018.07.014. Epub 2018 Jul 17. Bioorg Chem. 2018. PMID: 30059891
214 results