Leppla SH - Search Results

1

Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases.

Gordon VM, Leppla SH. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1994 Feb;62(2):333-40. doi: 10.1128/iai.62.2.333-340.1994. Infect Immun. 1994. PMID: 8300195 Free PMC article. Review. No abstract available.

2

Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.

Gordon VM, Young WW Jr, Lechler SM, Gray MC, Leppla SH, Hewlett EL. Gordon VM, et al. Among authors: leppla sh. J Biol Chem. 1989 Sep 5;264(25):14792-6. J Biol Chem. 1989. PMID: 2504710 Free article.

3

Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin.

Gordon VM, Leppla SH, Hewlett EL. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1988 May;56(5):1066-9. doi: 10.1128/iai.56.5.1066-1069.1988. Infect Immun. 1988. PMID: 2895741 Free PMC article.

4

Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases.

Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla SH. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1995 Jan;63(1):82-7. doi: 10.1128/iai.63.1.82-87.1995. Infect Immun. 1995. PMID: 7806387 Free PMC article.

5

In vitro processing of anthrax toxin protective antigen by recombinant PC1 (SPC3) and bovine intermediate lobe secretory vesicle membranes.

Friedman TC, Gordon VM, Leppla SH, Klimpel KR, Birch NP, Loh YP. Friedman TC, et al. Among authors: leppla sh. Arch Biochem Biophys. 1995 Jan 10;316(1):5-13. doi: 10.1006/abbi.1995.1002. Arch Biochem Biophys. 1995. PMID: 7840657

6

Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.

Arora N, Leppla SH. Arora N, et al. Among authors: leppla sh. Infect Immun. 1994 Nov;62(11):4955-61. doi: 10.1128/iai.62.11.4955-4961.1994. Infect Immun. 1994. PMID: 7927776 Free PMC article.

7

Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells.

Gu M, Gordon VM, Fitzgerald DJ, Leppla SH. Gu M, et al. Among authors: leppla sh. Infect Immun. 1996 Feb;64(2):524-7. doi: 10.1128/iai.64.2.524-527.1996. Infect Immun. 1996. PMID: 8550202 Free PMC article.

8

A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.

Gordon VM, Rehemtulla A, Leppla SH. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1997 Aug;65(8):3370-5. doi: 10.1128/iai.65.8.3370-3375.1997. Infect Immun. 1997. PMID: 9234799 Free PMC article.

9

Clostridium septicum alpha-toxin is proteolytically activated by furin.

Gordon VM, Benz R, Fujii K, Leppla SH, Tweten RK. Gordon VM, et al. Among authors: leppla sh. Infect Immun. 1997 Oct;65(10):4130-4. doi: 10.1128/iai.65.10.4130-4134.1997. Infect Immun. 1997. PMID: 9317018 Free PMC article.

10

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor.

Duesbery NS, Webb CP, Leppla SH, Gordon VM, Klimpel KR, Copeland TD, Ahn NG, Oskarsson MK, Fukasawa K, Paull KD, Vande Woude GF. Duesbery NS, et al. Among authors: leppla sh. Science. 1998 May 1;280(5364):734-7. doi: 10.1126/science.280.5364.734. Science. 1998. PMID: 9563949

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