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Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice.
Johnson SC, Yanos ME, Bitto A, Castanza A, Gagnidze A, Gonzalez B, Gupta K, Hui J, Jarvie C, Johnson BM, Letexier N, McCanta L, Sangesland M, Tamis O, Uhde L, Van Den Ende A, Rabinovitch PS, Suh Y, Kaeberlein M. Johnson SC, et al. Among authors: letexier n. Front Genet. 2015 Jul 22;6:247. doi: 10.3389/fgene.2015.00247. eCollection 2015. Front Genet. 2015. PMID: 26257774 Free PMC article.
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.
Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Bitto A, et al. Among authors: letexier nj. Elife. 2016 Aug 23;5:e16351. doi: 10.7554/eLife.16351. Elife. 2016. PMID: 27549339 Free PMC article.
Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice.
Rovira Gonzalez YI, Moyer AL, LeTexier NJ, Bratti AD, Feng S, Sun C, Liu T, Mula J, Jha P, Iyer SR, Lovering RM, O'Rourke B, Noh HL, Suk S, Kim JK, Essien Umanah GK, Wagner KR. Rovira Gonzalez YI, et al. Among authors: letexier nj. JCI Insight. 2019 Oct 17;4(20):e122247. doi: 10.1172/jci.insight.122247. JCI Insight. 2019. PMID: 31527314 Free PMC article.