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Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases.
Lewthwaite JC, Clarkin CE, Coates AR, Poole S, Lawrence RA, Wheeler-Jones CP, Pitsillides AA, Singh M, Henderson B. Lewthwaite JC, et al. Int Immunopharmacol. 2007 Feb;7(2):230-40. doi: 10.1016/j.intimp.2006.10.005. Epub 2006 Nov 20. Int Immunopharmacol. 2007. PMID: 17178391
Are molecular chaperones microbial virulence factors?
Lewthwaite J, Skinner A, Henderson B. Lewthwaite J, et al. Trends Microbiol. 1998 Nov;6(11):426-8. doi: 10.1016/s0966-842x(98)01362-6. Trends Microbiol. 1998. PMID: 9846353 Review. No abstract available.
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