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Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation.
Labrousse VF, Leyrolle Q, Amadieu C, Aubert A, Sere A, Coutureau E, Grégoire S, Bretillon L, Pallet V, Gressens P, Joffre C, Nadjar A, Layé S. Labrousse VF, et al. Among authors: leyrolle q. Brain Behav Immun. 2018 Oct;73:427-440. doi: 10.1016/j.bbi.2018.06.004. Epub 2018 Jun 4. Brain Behav Immun. 2018. PMID: 29879442
Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime.
Leyrolle Q, Decoeur F, Briere G, Amadieu C, Quadros ARAA, Voytyuk I, Lacabanne C, Benmamar-Badel A, Bourel J, Aubert A, Sere A, Chain F, Schwendimann L, Matrot B, Bourgeois T, Grégoire S, Leblanc JG, De Moreno De Leblanc A, Langella P, Fernandes GR, Bretillon L, Joffre C, Uricaru R, Thebault P, Gressens P, Chatel JM, Layé S, Nadjar A. Leyrolle Q, et al. Neuropsychopharmacology. 2021 Feb;46(3):579-602. doi: 10.1038/s41386-020-00793-7. Epub 2020 Aug 11. Neuropsychopharmacology. 2021. PMID: 32781459 Free PMC article.
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.
Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh AD, Delpech JC, Martinat M, Bosch-Bouju C, Bourel J, Rani B, Lacabanne C, Thomazeau A, Hopperton KE, Beccari S, Sere A, Aubert A, De Smedt-Peyrusse V, Lecours C, Bisht K, Fourgeaud L, Gregoire S, Bretillon L, Acar N, Grant NJ, Badaut J, Gressens P, Sierra A, Butovsky O, Tremblay ME, Bazinet RP, Joffre C, Nadjar A, Layé S. Madore C, et al. Among authors: leyrolle q. Nat Commun. 2020 Nov 30;11(1):6133. doi: 10.1038/s41467-020-19861-z. Nat Commun. 2020. PMID: 33257673 Free PMC article.
N-3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development.
Leyrolle Q, Decoeur F, Dejean C, Brière G, Leon S, Bakoyiannis I, Baroux E, Sterley TL, Bosch-Bouju C, Morel L, Amadieu C, Lecours C, St-Pierre MK, Bordeleau M, De Smedt-Peyrusse V, Séré A, Schwendimann L, Grégoire S, Bretillon L, Acar N, Joffre C, Ferreira G, Uricaru R, Thebault P, Gressens P, Tremblay ME, Layé S, Nadjar A. Leyrolle Q, et al. Glia. 2022 Jan;70(1):50-70. doi: 10.1002/glia.24088. Epub 2021 Sep 14. Glia. 2022. PMID: 34519378
Microbiota-derived metabolites as drivers of gut-brain communication.
Ahmed H, Leyrolle Q, Koistinen V, Kärkkäinen O, Layé S, Delzenne N, Hanhineva K. Ahmed H, et al. Among authors: leyrolle q. Gut Microbes. 2022 Jan-Dec;14(1):2102878. doi: 10.1080/19490976.2022.2102878. Gut Microbes. 2022. PMID: 35903003 Free PMC article.
Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner.
De Meij J, Alfanek Z, Morel L, Decoeur F, Leyrolle Q, Picard K, Carrier M, Aubert A, Séré A, Lucas C, Laforest G, Helbling JC, Tremblay ME, Cota D, Moisan MP, Marsicano G, Layé S, Nadjar A. De Meij J, et al. Among authors: leyrolle q. Cannabis Cannabinoid Res. 2021 Dec;6(6):488-507. doi: 10.1089/can.2020.0170. Epub 2021 Sep 29. Cannabis Cannabinoid Res. 2021. PMID: 34591647 Free PMC article.
24 results