Li H - Search Results

1

Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.

Hung CM, Calejman CM, Sanchez-Gurmaches J, Li H, Clish CB, Hettmer S, Wagers AJ, Guertin DA. Hung CM, et al. Among authors: li h. Cell Rep. 2014 Jul 10;8(1):256-71. doi: 10.1016/j.celrep.2014.06.007. Epub 2014 Jul 4. Cell Rep. 2014. PMID: 25001283 Free PMC article.

2

Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.

Li H, Cotton JL, Guertin DA. Li H, et al. Methods Mol Biol. 2012;821:329-47. doi: 10.1007/978-1-61779-430-8_21. Methods Mol Biol. 2012. PMID: 22125076

3

PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors.

Sanchez-Gurmaches J, Hung CM, Sparks CA, Tang Y, Li H, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: li h. Cell Metab. 2012 Sep 5;16(3):348-62. doi: 10.1016/j.cmet.2012.08.003. Cell Metab. 2012. PMID: 22940198 Free PMC article.

4

Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.

Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA. Tang Y, et al. Among authors: li h. Nat Commun. 2016 Apr 21;7:11365. doi: 10.1038/ncomms11365. Nat Commun. 2016. PMID: 27098609 Free PMC article.

5

Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease.

Lee PL, Tang Y, Li H, Guertin DA. Lee PL, et al. Among authors: li h. Mol Metab. 2016 Apr 11;5(6):422-432. doi: 10.1016/j.molmet.2016.04.001. eCollection 2016 Jun. Mol Metab. 2016. PMID: 27257602 Free PMC article.

6

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.

Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: li h. Cell Metab. 2018 Jan 9;27(1):195-209.e6. doi: 10.1016/j.cmet.2017.10.008. Epub 2017 Nov 16. Cell Metab. 2018. PMID: 29153407 Free PMC article.

7

Brown fat organogenesis and maintenance requires AKT1 and AKT2.

Sanchez-Gurmaches J, Martinez Calejman C, Jung SM, Li H, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: li h. Mol Metab. 2019 May;23:60-74. doi: 10.1016/j.molmet.2019.02.004. Epub 2019 Feb 20. Mol Metab. 2019. PMID: 30833219 Free PMC article.

8

Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.

Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, Metallo CM, Guertin DA. Jung SM, et al. Among authors: li h. Mol Cell. 2019 Aug 22;75(4):807-822.e8. doi: 10.1016/j.molcel.2019.07.023. Mol Cell. 2019. PMID: 31442424 Free PMC article.

9

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. Martinez Calejman C, et al. Among authors: li h. Nat Commun. 2020 Jan 29;11(1):575. doi: 10.1038/s41467-020-14430-w. Nat Commun. 2020. PMID: 31996678 Free PMC article.

10

Author Correction: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

Calejman CM, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. Calejman CM, et al. Among authors: li h. Nat Commun. 2020 Sep 8;11(1):4585. doi: 10.1038/s41467-020-18510-9. Nat Commun. 2020. PMID: 32901020 Free PMC article.

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