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Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes.
Li J, Wang H, Rosenberg PA. Li J, et al. J Neurosci Res. 2009 Jul;87(9):1997-2005. doi: 10.1002/jnr.22029. J Neurosci Res. 2009. PMID: 19235890 Free PMC article.
We previously demonstrated a novel function of phylloquinone (vitamin K(1)) and menaquinone 4 (MK-4; a major form of vitamin K2) in protecting pre-OLs and immature neurons against glutathione depletion-induced oxidative damage (Li et al. [ 2003] J. Neurosci. 23:5816 …
We previously demonstrated a novel function of phylloquinone (vitamin K(1)) and menaquinone 4 (MK-4; a major form of vitamin K2) in protecti …
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