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Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits.
Hao J, Fan W, Li Y, Tang R, Tian C, Yang Q, Zhu T, Diao C, Hu S, Chen M, Guo P, Long Q, Zhang C, Qin G, Yu W, Chen M, Li L, Qin L, Wang J, Zhang X, Ren Y, Zhou P, Zou L, Jiang K, Guo W, Deng W. Hao J, et al. Among authors: li y, li l. J Exp Clin Cancer Res. 2019 Feb 4;38(1):48. doi: 10.1186/s13046-019-1036-z. J Exp Clin Cancer Res. 2019. PMID: 30717768 Free PMC article.
Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway.
Liu T, Jin L, Chen M, Zheng Z, Lu W, Fan W, Li L, Zheng F, Zhu Q, Qiu H, Liu J, Chen M, Tian C, Hu Z, Zhang C, Luo M, Li J, Kang T, Yang L, Li Y, Deng W. Liu T, et al. Among authors: li y, li j, li l. Redox Biol. 2019 Jul;25:101197. doi: 10.1016/j.redox.2019.101197. Epub 2019 Apr 20. Redox Biol. 2019. PMID: 31023624 Free PMC article.
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Yang Q, Fan W, Zheng Z, Lin S, Liu C, Wang R, Li W, Zuo Y, Sun Y, Hu S, Chen M, Guo P, Pan J, Tian C, Zhu T, Diao C, Hao J, Yu W, Li L, Li Y, Guo W, Deng W, Wu X. Yang Q, et al. Among authors: li y, li w, li l. Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1533-1543. doi: 10.1016/j.bbamcr.2019.07.001. Epub 2019 Jul 10. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 31301362 Free article.
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