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Discovery of High-Affinity Inhibitors of the BPTF Bromodomain.
Lu T, Lu H, Duan Z, Wang J, Han J, Xiao S, Chen H, Jiang H, Chen Y, Yang F, Li Q, Chen D, Lin J, Li B, Jiang H, Chen K, Lu W, Lin H, Luo C. Lu T, et al. Among authors: li q, li b. J Med Chem. 2021 Aug 26;64(16):12075-12088. doi: 10.1021/acs.jmedchem.1c00721. Epub 2021 Aug 10. J Med Chem. 2021. PMID: 34375106
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3.
Lu T, Li Y, Lu W, Spitters T, Fang X, Wang J, Cai S, Gao J, Zhou Y, Duan Z, Xiong H, Liu L, Li Q, Jiang H, Chen K, Zhou H, Lin H, Feng H, Zhou B, Antos CL, Luo C. Lu T, et al. Among authors: li y, li q. Acta Pharm Sin B. 2021 Oct;11(10):3206-3219. doi: 10.1016/j.apsb.2021.04.015. Epub 2021 May 1. Acta Pharm Sin B. 2021. PMID: 34729310 Free PMC article.
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib.
Zhou XR, Li X, Liao LP, Han J, Huang J, Li JC, Tao HR, Fan SJ, Chen ZF, Li Q, Chen SJ, Ding H, Yang YX, Zhou B, Jiang HL, Chen KX, Zhang YY, Huang CX, Luo C. Zhou XR, et al. Among authors: li x, li q, li jc. Acta Pharmacol Sin. 2022 Feb;43(2):457-469. doi: 10.1038/s41401-021-00643-2. Epub 2021 Apr 13. Acta Pharmacol Sin. 2022. PMID: 33850273 Free PMC article.
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.
Huang Y, Yan J, Li Q, Li J, Gong S, Zhou H, Gan J, Jiang H, Jia GF, Luo C, Yang CG. Huang Y, et al. Among authors: li j, li q. Nucleic Acids Res. 2015 Jan;43(1):373-84. doi: 10.1093/nar/gku1276. Epub 2014 Dec 1. Nucleic Acids Res. 2015. PMID: 25452335 Free PMC article.
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