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The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Zorgati H, Larsson M, Ren W, Sim AYL, Gettemans J, Grimes JM, Li W, Robinson RC. Zorgati H, et al. Among authors: li w. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13958-13963. doi: 10.1073/pnas.1902189116. Epub 2019 Jun 26. Proc Natl Acad Sci U S A. 2019. PMID: 31243148 Free PMC article.
Role of substrate-product frustration on enzyme functional dynamics.
Kong J, Li J, Lu J, Li W, Wang W. Kong J, et al. Among authors: li j, li w. Phys Rev E. 2019 Nov;100(5-1):052409. doi: 10.1103/PhysRevE.100.052409. Phys Rev E. 2019. PMID: 31869999
Our recent work demonstrated that multisubstrate enzymes can utilize steric frustration encountered in the substrate-product cobound complex to overcome the bottleneck of the enzymatic cycle [W. Li et al., Phys. Rev. Lett. 122, 238102 (2019)10.1103/PhysRevLett.122.2 …
Our recent work demonstrated that multisubstrate enzymes can utilize steric frustration encountered in the substrate-product cobound complex …
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