Li YM - Search Results

1

High-throughput identification of inhibitors of human mitochondrial peptide deformylase.

Antczak C, Shum D, Escobar S, Bassit B, Kim E, Seshan VE, Wu N, Yang G, Ouerfelli O, Li YM, Scheinberg DA, Djaballah H. Antczak C, et al. Among authors: li ym. J Biomol Screen. 2007 Jun;12(4):521-35. doi: 10.1177/1087057107300463. Epub 2007 Apr 13. J Biomol Screen. 2007. PMID: 17435169 Free PMC article.

2

A new human peptide deformylase inhibitable by actinonin.

Lee MD, Antczak C, Li Y, Sirotnak FM, Bornmann WG, Scheinberg DA. Lee MD, et al. Biochem Biophys Res Commun. 2003 Dec 12;312(2):309-15. doi: 10.1016/j.bbrc.2003.10.123. Biochem Biophys Res Commun. 2003. PMID: 14637138

3

Stereoselective synthesis of photoreactive peptidomimetic gamma-secretase inhibitors.

Chun J, Yin YI, Yang G, Tarassishin L, Li YM. Chun J, et al. Among authors: li ym. J Org Chem. 2004 Oct 15;69(21):7344-7. doi: 10.1021/jo0486948. J Org Chem. 2004. PMID: 15471490

4

Processing of Notch and amyloid precursor protein by gamma-secretase is spatially distinct.

Tarassishin L, Yin YI, Bassit B, Li YM. Tarassishin L, et al. Among authors: li ym. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17050-5. doi: 10.1073/pnas.0408007101. Epub 2004 Nov 24. Proc Natl Acad Sci U S A. 2004. PMID: 15563588 Free PMC article.

5

{gamma}-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: IMPLICATIONS FOR ALZHEIMER DISEASE.

Yin YI, Bassit B, Zhu L, Yang X, Wang C, Li YM. Yin YI, et al. Among authors: li ym. J Biol Chem. 2007 Aug 10;282(32):23639-44. doi: 10.1074/jbc.M704601200. Epub 2007 Jun 7. J Biol Chem. 2007. PMID: 17556361 Free article.

6

Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.

Placanica L, Tarassishin L, Yang G, Peethumnongsin E, Kim SH, Zheng H, Sisodia SS, Li YM. Placanica L, et al. Among authors: li ym. J Biol Chem. 2009 Jan 30;284(5):2967-2977. doi: 10.1074/jbc.M807269200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19036728 Free PMC article.

7

Stereo-controlled synthesis of novel photoreactive gamma-secretase inhibitors.

Yang G, Yin YI, Chun J, Shelton CC, Ouerfelli O, Li YM. Yang G, et al. Among authors: li ym. Bioorg Med Chem Lett. 2009 Feb 1;19(3):922-5. doi: 10.1016/j.bmcl.2008.11.117. Epub 2008 Dec 7. Bioorg Med Chem Lett. 2009. PMID: 19097779 Free PMC article.

8

Structure and activity of human mitochondrial peptide deformylase, a novel cancer target.

Escobar-Alvarez S, Goldgur Y, Yang G, Ouerfelli O, Li Y, Scheinberg DA. Escobar-Alvarez S, et al. J Mol Biol. 2009 Apr 17;387(5):1211-28. doi: 10.1016/j.jmb.2009.02.032. Epub 2009 Feb 21. J Mol Biol. 2009. PMID: 19236878 Free PMC article.

9

A miniaturized 1536-well format gamma-secretase assay.

Shelton CC, Tian Y, Shum D, Radu C, Djaballah H, Li YM. Shelton CC, et al. Among authors: li ym. Assay Drug Dev Technol. 2009 Oct;7(5):461-70. doi: 10.1089/adt.2009.0202. Assay Drug Dev Technol. 2009. PMID: 19715456 Free PMC article.

10

Modulation of gamma-secretase specificity using small molecule allosteric inhibitors.

Shelton CC, Zhu L, Chau D, Yang L, Wang R, Djaballah H, Zheng H, Li YM. Shelton CC, et al. Among authors: li ym. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20228-33. doi: 10.1073/pnas.0910757106. Epub 2009 Nov 11. Proc Natl Acad Sci U S A. 2009. PMID: 19906985 Free PMC article.

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