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A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks.
Fang EF, Xie C, Schenkel JA, Wu C, Long Q, Cui H, Aman Y, Frank J, Liao J, Zou H, Wang NY, Wu J, Liu X, Li T, Fang Y, Niu Z, Yang G, Hong J, Wang Q, Chen G, Li J, Chen HZ, Kang L, Su H, Gilmour BC, Zhu X, Jiang H, He N, Tao J, Leng SX, Tong T, Woo J. Fang EF, et al. Ageing Res Rev. 2020 Dec;64:101174. doi: 10.1016/j.arr.2020.101174. Epub 2020 Sep 21. Ageing Res Rev. 2020. PMID: 32971255 Free PMC article. Review.
Researchers are striving to produce drugs that can mimic the effects of 'exercising more, eating less', while other anti-ageing molecules from molecular gerontologists could help to improve 'healthspan' in the elderly. ...
Researchers are striving to produce drugs that can mimic the effects of 'exercising more, eating less', while other anti-ageing molecules …
Advances of Anti-Caries Nanomaterials.
Chen H, Gu L, Liao B, Zhou X, Cheng L, Ren B. Chen H, et al. Molecules. 2020 Oct 30;25(21):5047. doi: 10.3390/molecules25215047. Molecules. 2020. PMID: 33143140 Free PMC article. Review.
Recent advances in the oxime-participating synthesis of isoxazolines.
Liao J, Ouyang L, Jin Q, Zhang J, Luo R. Liao J, et al. Org Biomol Chem. 2020 Jul 1;18(25):4709-4716. doi: 10.1039/d0ob00963f. Org Biomol Chem. 2020. PMID: 32525196 Review.
Isoxazoline compounds are used as important intermediates for the synthesis of organic molecules, which are widely used in the chemical and life science industries. ...
Isoxazoline compounds are used as important intermediates for the synthesis of organic molecules, which are widely used in the chemic …
The immuno-reactivity of polypseudorotaxane functionalized magnetic CDMNP-PEG-CD nanoparticles.
Lan H, Huang T, Xiao J, Liao Z, Ouyang J, Dong J, Xian CJ, Hu J, Wang L, Ke Y, Liao H. Lan H, et al. J Cell Mol Med. 2021 Jan;25(1):561-574. doi: 10.1111/jcmm.16109. Epub 2020 Nov 19. J Cell Mol Med. 2021. PMID: 33210833 Free PMC article.
Recently, a polypseudorotaxane functionalized magnetic nanoparticle (MNP) was developed by synthesizing the magnetic nanoparticles with cyclodextrin (CD) molecules (CDMNP) via polyethylene glycol (PEG) (CDMNP-PEG-CD). The purpose of this study was to explore the antigenici …
Recently, a polypseudorotaxane functionalized magnetic nanoparticle (MNP) was developed by synthesizing the magnetic nanoparticles with cycl …
Mitochondria-targeted Re(I) complexes bearing guanidinium as ligands and their anticancer activity.
He SF, Pan NL, Chen BB, Liao JX, Huang MY, Qiu HJ, Jiang DC, Wang JJ, Chen JX, Sun J. He SF, et al. J Biol Inorg Chem. 2020 Dec;25(8):1107-1116. doi: 10.1007/s00775-020-01827-7. Epub 2020 Oct 20. J Biol Inorg Chem. 2020. PMID: 33079244
As the "powerhouse" of a cell, mitochondria maintain energy homeostasis, synthesize ATP via oxidative phosphorylation, generate ROS signaling molecules, and modulate cell apoptosis. Herein, three Re(I) complexes bearing guanidinium derivatives have been synthesized and cha …
As the "powerhouse" of a cell, mitochondria maintain energy homeostasis, synthesize ATP via oxidative phosphorylation, generate ROS signalin …
A platinum-nickel bimetallic nanocluster ensemble-on-polyaniline nanofilm for enhanced electrocatalytic oxidation of dopamine.
Yadav A , Pandey R , Liao TW , Zharinov VS , Hu KJ , Vernieres J , Palmer RE , Lievens P , Grandjean D , Shacham-Diamand Y . Yadav A , et al. Nanoscale. 2020 Mar 14;12(10):6047-6056. doi: 10.1039/c9nr09730a. Epub 2020 Mar 4. Nanoscale. 2020. PMID: 32129392
We report a new approach to design flexible functional material platforms based on electropolymerized polyaniline (PANI) polymer nanofilms modified with bimetallic nanoclusters (NCs) for efficient electro-oxidation of small organic molecules. Composition defined ligand fre …
We report a new approach to design flexible functional material platforms based on electropolymerized polyaniline (PANI) polymer nanofilms m …
Serum levels of cell adhesion molecules in patients with neuromyelitis optica spectrum disorder.
Chang BL, Ro LS, Chen CM, Lo YS, Lyu RK, Kuo HC, Liao MF, Chang CW, Chang HS, Huang CC, Wu YR, Chu CC, Weng YC, Chang KH. Chang BL, et al. Ann Clin Transl Neurol. 2020 Oct;7(10):1854-1861. doi: 10.1002/acn3.51167. Epub 2020 Aug 28. Ann Clin Transl Neurol. 2020. PMID: 32860355 Free PMC article.
OBJECTIVES: Blood-brain barrier (BBB) disruption is a critical pathological process involved in neuromyelitis optica spectrum disorder (NMOSD). Here, we characterized the profile of five cell adhesion molecules in patients with NMOSD. METHODS: We measured levels of cell ad …
OBJECTIVES: Blood-brain barrier (BBB) disruption is a critical pathological process involved in neuromyelitis optica spectrum disorder (NMOS …
High-Scalable Collaborated Parallel Framework for Large-Scale Molecular Dynamic Simulation on Tianhe-2 Supercomputer.
Peng S, Zhang X, Su W, Dong D, Lu Y, Liao X, Lu K, Yang C, Liu J, Zhu W, Wei D. Peng S, et al. IEEE/ACM Trans Comput Biol Bioinform. 2020 May-Jun;17(3):804-816. doi: 10.1109/TCBB.2018.2805709. Epub 2018 Feb 13. IEEE/ACM Trans Comput Biol Bioinform. 2020. PMID: 29994638
Molecular dynamics (MD) is a computer simulation method of studying physical movements of atoms and molecules that provide detailed microscopic sampling on molecular scale. ...By the three levels of parallel acceleration strategy above, we achieved the highest speedup of …
Molecular dynamics (MD) is a computer simulation method of studying physical movements of atoms and molecules that provide detailed m …
46 results