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CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.
Vinyard ME, Su C, Siegenfeld AP, Waterbury AL, Freedy AM, Gosavi PM, Park Y, Kwan EE, Senzer BD, Doench JG, Bauer DE, Pinello L, Liau BB. Vinyard ME, et al. Among authors: liau bb. Nat Chem Biol. 2019 May;15(5):529-539. doi: 10.1038/s41589-019-0263-0. Epub 2019 Apr 15. Nat Chem Biol. 2019. PMID: 30992567 Free PMC article.
Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, Si C, Ebmeier CC, Bronson RT, Krivtsov AV, Myers AG, Kohl NE, Kung AL, Armstrong SA, Lemieux ME, Taatjes DJ, Shair MD. Pelish HE, et al. Among authors: liau bb. Nature. 2015 Oct 8;526(7572):273-276. doi: 10.1038/nature14904. Epub 2015 Sep 28. Nature. 2015. PMID: 26416749 Free PMC article.
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE. Flavahan WA, et al. Among authors: liau bb. Nature. 2016 Jan 7;529(7584):110-4. doi: 10.1038/nature16490. Epub 2015 Dec 23. Nature. 2016. PMID: 26700815 Free PMC article.
Uncovering the Cellular Target of Agelastatin A.
Park Y, Liau BB. Park Y, et al. Among authors: liau bb. Cell Chem Biol. 2017 May 18;24(5):542-543. doi: 10.1016/j.chembiol.2017.05.002. Cell Chem Biol. 2017. PMID: 28525767 Free article.
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. Miller TE, et al. Among authors: liau bb. Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5. Nature. 2017. PMID: 28678782 Free PMC article.
Taking a STAP at Core Promoter-Transcriptional Cofactor Specificity.
Siegenfeld AP, Lee C, Liau BB. Siegenfeld AP, et al. Among authors: liau bb. Biochemistry. 2019 Jul 23;58(29):3133-3135. doi: 10.1021/acs.biochem.9b00537. Epub 2019 Jul 12. Biochemistry. 2019. PMID: 31298845 Review. No abstract available.
Discovering new biology with drug-resistance alleles.
Freedy AM, Liau BB. Freedy AM, et al. Among authors: liau bb. Nat Chem Biol. 2021 Dec;17(12):1219-1229. doi: 10.1038/s41589-021-00865-9. Epub 2021 Nov 19. Nat Chem Biol. 2021. PMID: 34799733 Free PMC article. Review.
41 results