Lim D - Search Results

1

Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.

Liu F, Park JE, Qian WJ, Lim D, Scharow A, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: lim d. Chembiochem. 2012 Jun 18;13(9):1291-6. doi: 10.1002/cbic.201200206. Epub 2012 May 8. Chembiochem. 2012. PMID: 22570300 Free PMC article.

2

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel.

Liu F, Park JE, Qian WJ, Lim D, Gräber M, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: lim d. Nat Chem Biol. 2011 Jul 17;7(9):595-601. doi: 10.1038/nchembio.614. Nat Chem Biol. 2011. PMID: 21765407 Free PMC article.

3

Identification of high affinity polo-like kinase 1 (Plk1) polo-box domain binding peptides using oxime-based diversification.

Liu F, Park JE, Qian WJ, Lim D, Scharow A, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: lim d. ACS Chem Biol. 2012 May 18;7(5):805-10. doi: 10.1021/cb200469a. Epub 2012 Feb 14. ACS Chem Biol. 2012. PMID: 22292814 Free PMC article.

4

Peptide-based inhibitors of Plk1 polo-box domain containing mono-anionic phosphothreonine esters and their pivaloyloxymethyl prodrugs.

Qian WJ, Park JE, Lim D, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr. Qian WJ, et al. Among authors: lim d. Chem Biol. 2013 Oct 24;20(10):1255-64. doi: 10.1016/j.chembiol.2013.09.005. Epub 2013 Oct 10. Chem Biol. 2013. PMID: 24120332 Free PMC article. Retracted.

5

Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high Plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in HeLa cells.

Qian WJ, Park JE, Lim D, Lai CC, Kelley JA, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr. Qian WJ, et al. Among authors: lim d. Biopolymers. 2014 Nov;102(6):444-55. doi: 10.1002/bip.22569. Biopolymers. 2014. PMID: 25283071 Free PMC article.

6

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.

Ryu S, Park JE, Ham YJ, Lim DC, Kwiatkowski NP, Kim DH, Bhunia D, Kim ND, Yaffe MB, Son W, Kim N, Choi TI, Swain P, Kim CH, Lee JY, Gray NS, Lee KS, Sim T. Ryu S, et al. Among authors: lim dc. J Med Chem. 2022 Feb 10;65(3):1915-1932. doi: 10.1021/acs.jmedchem.1c01359. Epub 2022 Jan 14. J Med Chem. 2022. PMID: 35029981 Free PMC article.

7

Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.

Lowery DM, Clauser KR, Hjerrild M, Lim D, Alexander J, Kishi K, Ong SE, Gammeltoft S, Carr SA, Yaffe MB. Lowery DM, et al. Among authors: lim d. EMBO J. 2007 May 2;26(9):2262-73. doi: 10.1038/sj.emboj.7601683. Epub 2007 Apr 19. EMBO J. 2007. PMID: 17446864 Free PMC article.

8

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.

Yun SM, Moulaei T, Lim D, Bang JK, Park JE, Shenoy SR, Liu F, Kang YH, Liao C, Soung NK, Lee S, Yoon DY, Lim Y, Lee DH, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR Jr, Yaffe MB, Wlodawer A, Lee KS. Yun SM, et al. Among authors: lim d, lim y. Nat Struct Mol Biol. 2009 Aug;16(8):876-82. doi: 10.1038/nsmb.1628. Epub 2009 Jul 13. Nat Struct Mol Biol. 2009. PMID: 19597481 Free PMC article.

9

Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.

Murugan RN, Park JE, Lim D, Ahn M, Cheong C, Kwon T, Nam KY, Choi SH, Kim BY, Yoon DY, Yaffe MB, Yu DY, Lee KS, Bang JK. Murugan RN, et al. Among authors: lim d. Bioorg Med Chem. 2013 May 1;21(9):2623-34. doi: 10.1016/j.bmc.2013.02.020. Epub 2013 Feb 27. Bioorg Med Chem. 2013. PMID: 23498919 Free PMC article.

10

Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence.

Lim D, Gold DA, Julien L, Rosowski EE, Niedelman W, Yaffe MB, Saeij JP. Lim D, et al. J Biol Chem. 2013 Nov 29;288(48):34968-80. doi: 10.1074/jbc.M113.523266. Epub 2013 Oct 15. J Biol Chem. 2013. PMID: 24129568 Free PMC article.

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