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Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF.
Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA. Murphy EA, et al. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4299-304. doi: 10.1073/pnas.0909299107. Epub 2010 Feb 12. Proc Natl Acad Sci U S A. 2010. PMID: 20154271 Free PMC article.
Derivation of vasculature from embryonic stem cells.
Lindquist JN, Cheresh DA, Snyder EY. Lindquist JN, et al. Curr Protoc Stem Cell Biol. 2010 Mar;Chapter 1:Unit 1F.9. doi: 10.1002/9780470151808.sc01f09s12. Curr Protoc Stem Cell Biol. 2010. PMID: 20200855
Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.
Jadhavar PS, Ramachandran SA, Riquelme E, Gupta A, Quinn KP, Shivakumar D, Ray S, Zende D, Nayak AK, Miglani SK, Sathe BD, Raja M, Farias O, Alfaro I, Belmar S, Guerrero J, Bernales S, Chakravarty S, Hung DT, Lindquist JN, Rai R. Jadhavar PS, et al. Among authors: lindquist jn. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. doi: 10.1016/j.bmcl.2016.09.058. Epub 2016 Oct 4. Bioorg Med Chem Lett. 2016. PMID: 27717544
22 results