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Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Kayatekin C, Matlack KE, Hesse WR, Guan Y, Chakrabortee S, Russ J, Wanker EE, Shah JV, Lindquist S. Kayatekin C, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12085-90. doi: 10.1073/pnas.1412504111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092318 Free PMC article.
Luminidependens (LD) is an Arabidopsis protein with prion behavior.
Chakrabortee S, Kayatekin C, Newby GA, Mendillo ML, Lancaster A, Lindquist S. Chakrabortee S, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2016 May 24;113(21):6065-70. doi: 10.1073/pnas.1604478113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114519 Free PMC article.
A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.
Newby GA, Kiriakov S, Hallacli E, Kayatekin C, Tsvetkov P, Mancuso CP, Bonner JM, Hesse WR, Chakrabortee S, Manogaran AL, Liebman SW, Lindquist S, Khalil AS. Newby GA, et al. Among authors: lindquist s. Cell. 2017 Nov 2;171(4):966-979.e18. doi: 10.1016/j.cell.2017.09.041. Epub 2017 Oct 19. Cell. 2017. PMID: 29056345 Free PMC article.
A network of protein interactions determines polyglutamine toxicity.
Duennwald ML, Jagadish S, Giorgini F, Muchowski PJ, Lindquist S. Duennwald ML, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11051-6. doi: 10.1073/pnas.0604548103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832049 Free PMC article.
Flanking sequences profoundly alter polyglutamine toxicity in yeast.
Duennwald ML, Jagadish S, Muchowski PJ, Lindquist S. Duennwald ML, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11045-50. doi: 10.1073/pnas.0604547103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832050 Free PMC article.
Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity.
Kayatekin C, Amasino A, Gaglia G, Flannick J, Bonner JM, Fanning S, Narayan P, Barrasa MI, Pincus D, Landgraf D, Nelson J, Hesse WR, Costanzo M; AMP T2D-GENES Consortium; Myers CL, Boone C, Florez JC, Lindquist S. Kayatekin C, et al. Among authors: lindquist s. Cell. 2018 Mar 22;173(1):62-73.e9. doi: 10.1016/j.cell.2018.02.026. Epub 2018 Mar 8. Cell. 2018. PMID: 29526462 Free PMC article.
463 results