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Page 1
New Insight into Justicidin B Pathway and Production in Linum austriacum.
Mascheretti I, Alfieri M, Lauria M, Locatelli F, Consonni R, Cusano E, Dougué Kentsop RA, Laura M, Ottolina G, Faoro F, Mattana M. Mascheretti I, et al. Int J Mol Sci. 2021 Mar 2;22(5):2507. doi: 10.3390/ijms22052507. Int J Mol Sci. 2021. PMID: 33801525 Free PMC article.
In this work, Linum austriacum in vitro cultures, cells (Cc), adventitious roots (ARc) and hairy roots (HRc) were developed for the production of justicidin B through elicitation with methyl jasmonate (MeJA) and coronatine (COR). ...Altogether, our results improve k …
In this work, Linum austriacum in vitro cultures, cells (Cc), adventitious roots (ARc) and hairy roots (HRc) were developed fo …
Arylnaphthalene Lignans with Anti-SARS-CoV-2 and Antiproliferative Activities from the Underground Organs of Linum austriacum and Linum perenne.
Tóth G, Horváti K, Kraszni M, Ausbüttel T, Pályi B, Kis Z, Mucsi Z, Kovács GM, Bősze S, Boldizsár I. Tóth G, et al. J Nat Prod. 2023 Apr 28;86(4):672-682. doi: 10.1021/acs.jnatprod.2c00580. Epub 2023 Mar 1. J Nat Prod. 2023. PMID: 36857518
To evaluate the in vitro antiviral and cytotoxic potency of both lignans in SARS-CoV-2 -infected cells and various cancer cell lines, respectively, 1 and 2 were isolated from the underground organs of Linum austriacum and Linum perenne. Two previously undescr …
To evaluate the in vitro antiviral and cytotoxic potency of both lignans in SARS-CoV-2 -infected cells and various cancer cell lines, respec …
Arylnaphthalene lignans from in vitro cultures of Linum austriacum.
Mohagheghzadeh A, Schmidt TJ, Alfermann AW. Mohagheghzadeh A, et al. J Nat Prod. 2002 Jan;65(1):69-71. doi: 10.1021/np0102814. J Nat Prod. 2002. PMID: 11809070
Callus, suspension, and normal and hairy root cultures of Linum austriacum produced a new arylnaphthalene lignan, 3,4-dimethoxy-3',4'-methylenedioxy-2,7'-cycloligna-7,7'-dieno-9,9'-lactone (1, 0.03-0.73% dry wt), together with justicidin B (2, 0.18-1.69% dry wt). .. …
Callus, suspension, and normal and hairy root cultures of Linum austriacum produced a new arylnaphthalene lignan, 3,4-dimethox …
Optimized Ultrasound-Assisted Extraction of Lignans from Linum Species with Green Solvents.
Alfieri M, Mascheretti I, Dougué Kentsop RA, Mattana M, Laura M, Ottolina G. Alfieri M, et al. Molecules. 2022 Apr 23;27(9):2732. doi: 10.3390/molecules27092732. Molecules. 2022. PMID: 35566080 Free PMC article.
Lignans can be obtained by plant in vitro cultures; their production by adventitious and hairy roots of Linum species seems to be a promising alternative to chemical synthesis. ...Finally, the optimal experimental conditions to extract justicidin B from L. austriacum …
Lignans can be obtained by plant in vitro cultures; their production by adventitious and hairy roots of Linum species seems to be a p …
Accumulation of lignans by in vitro cultures of three Linum species.
Mohagheghzadeh A, Dehshahri S, Hemmati S. Mohagheghzadeh A, et al. Z Naturforsch C J Biosci. 2009 Jan-Feb;64(1-2):73-6. doi: 10.1515/znc-2009-1-213. Z Naturforsch C J Biosci. 2009. PMID: 19323270 Free article.
Justicidin B, an arylnaphthalene lignan, has strong cytotoxicity on chronic myeloid and chronic lymphoid leukemia cell lines. The first report of the production of justicidin B in a Linum species concerned in vitro culture of Linum austriacum. Therefore, cult …
Justicidin B, an arylnaphthalene lignan, has strong cytotoxicity on chronic myeloid and chronic lymphoid leukemia cell lines. The first repo …
Lignans from Linum species of sections Syllinum and Linum.
Konuklugil B, Ionkova I, Vasilev N, Schmidt TJ, Windhövel J, Fuss E, Alfermann AW. Konuklugil B, et al. Nat Prod Res. 2007 Jan;21(1):1-6. doi: 10.1080/14786410600798385. Nat Prod Res. 2007. PMID: 17365680
The aryltetralin lignans 6-methoxypodophyllotoxin, 5'-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8'-epimers 6-methoxypicropodophyllin, and 5'-demethoxy-6-methoxypicropodophyllin were isolated from suspension cultures of Linum cariense, and 4'-demethyl- …
The aryltetralin lignans 6-methoxypodophyllotoxin, 5'-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8'-epimers 6-methoxypi …
Bag culture: a method for root-root co-culture.
Mohagheghzadeh A, Gholami A, Hemmati S, Dehshahri S. Mohagheghzadeh A, et al. Z Naturforsch C J Biosci. 2008 Jan-Feb;63(1-2):157-60. doi: 10.1515/znc-2008-1-229. Z Naturforsch C J Biosci. 2008. PMID: 18386507 Free article.
A method named "bag culture" was developed for coculturing of Linum persicum (section Syllinum) and L. austriacum (section Linum) hairy roots. For this propose L. austriacum and L. persicum hairy root cultures were established using Agrobacterium rhizo …
A method named "bag culture" was developed for coculturing of Linum persicum (section Syllinum) and L. austriacum (section …
[Comparative study of genomes of two species of flax by C-banding of chromosomes].
Muravenko OV, Samatadze TE, Popov KV, Amosova AV, Zelenii AV. Muravenko OV, et al. Genetika. 2001 Mar;37(3):332-5. Genetika. 2001. PMID: 11357365 Russian.
C-banding patterns of the karyotypes of two closely related wild flax species, Linum austriacum L. (2n = 18) and Linum grandiflorum Desf. (2n = 16), were studied. ...Apparently, the doubling of chromosome number or loss of one chromosome with subsequen …
C-banding patterns of the karyotypes of two closely related wild flax species, Linum austriacum L. (2n = 18) and Lin …
[Chromosomal localization of 5S and 45S ribosomal DNA in species of Linum L. section Linum (syn=Protolinum and Adenolinum)].
Muravenko OV, Amosova AV, Samatadze TE, Semenova OIu, Nosova IV, Popov KV, Shostak NG, Zoshchuk SA, Zelenin AV. Muravenko OV, et al. Genetika. 2004 Feb;40(2):256-60. Genetika. 2004. PMID: 15065434 Russian.
Fluorescence in situ hybridization (FISH) was for the first time used to study the chromosomal location of the 45S (18-2.5S-26S) and 5S ribosomal genes in the genomes of five flax species of the section Linum (syn. Protolinum and Adenolinum). ...Sites of 5S rDNA col …
Fluorescence in situ hybridization (FISH) was for the first time used to study the chromosomal location of the 45S (18-2.5S-26S) and 5S ribo …