Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 5
1953 4
1954 9
1955 7
1956 6
1957 7
1958 11
1959 21
1960 18
1961 21
1962 24
1963 54
1964 37
1965 18
1966 4
1967 12
1968 7
1969 7
1970 8
1971 3
1972 4
1973 4
1974 5
1975 12
1976 16
1977 22
1978 10
1979 13
1980 14
1981 16
1982 12
1983 9
1984 17
1985 8
1986 14
1987 8
1988 11
1989 20
1990 23
1991 18
1992 30
1993 30
1994 30
1995 41
1996 37
1997 52
1998 43
1999 87
2000 77
2001 91
2002 104
2003 129
2004 135
2005 146
2006 173
2007 194
2008 208
2009 193
2010 227
2011 258
2012 240
2013 317
2014 286
2015 293
2016 284
2017 304
2018 298
2019 297
2020 352
2021 329
2022 328
2023 313
2024 155

Text availability

Article attribute

Article type

Publication date

Search Results

5,901 results

Results by year

Filters applied: . Clear all
Page 1
Lipoic acid metabolism and mitochondrial redox regulation.
Solmonson A, DeBerardinis RJ. Solmonson A, et al. J Biol Chem. 2018 May 18;293(20):7522-7530. doi: 10.1074/jbc.TM117.000259. Epub 2017 Nov 30. J Biol Chem. 2018. PMID: 29191830 Free PMC article. Review.
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochondrial fatty-acid synthesis type II, S-adenosylmethionine and iron-sulfur clusters. ...Many of these dehydrogenases are regulated by reactive …
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochon …
Effect of Alpha-Lipoic Acid in the Treatment of Diabetic Neuropathy: A Systematic Review.
Abubaker SA, Alonazy AM, Abdulrahman A. Abubaker SA, et al. Cureus. 2022 Jun 8;14(6):e25750. doi: 10.7759/cureus.25750. eCollection 2022 Jun. Cureus. 2022. PMID: 35812639 Free PMC article. Review.
Novel studies have proposed that the use of antioxidants, including alpha-lipoic acid (-lipoic acid), may represent a beneficial intervention for treating neuropathic pain in diabetic patients. ...All studies found -lipoic acid to be a sa …
Novel studies have proposed that the use of antioxidants, including alpha-lipoic acid (-lipoic acid), may repres …
Alpha Lipoic Acid.
[No authors listed] [No authors listed] 2023 May 3. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 May 3. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 37184197 Free Books & Documents. Review.
Alpha lipoic acid is a natural occurring essential fatty acid that is synthesized intracellularly, but is also in many foods and absorbed to a variable extent. Alpha lipoic acid is a common ingredient in multivitamin tablets and in dietary supplements …
Alpha lipoic acid is a natural occurring essential fatty acid that is synthesized intracellularly, but is also in many foods a …
Advances in synthesis of biotin and assembly of lipoic acid.
Cronan JE. Cronan JE. Curr Opin Chem Biol. 2018 Dec;47:60-66. doi: 10.1016/j.cbpa.2018.08.004. Epub 2018 Sep 17. Curr Opin Chem Biol. 2018. PMID: 30236800 Free PMC article. Review.
Although biotin and lipoic acid are two universally conserved cofactors essential for intermediary metabolism, their synthetic pathways have become known only in recent years. ...Biotin synthesis in Escherichia coli requires a methylation that is later removed where …
Although biotin and lipoic acid are two universally conserved cofactors essential for intermediary metabolism, their synthetic …
Hypersensitivity to lipoic acid.
Marchi F, Carabelli A. Marchi F, et al. Eur Ann Allergy Clin Immunol. 2023 Sep 6. doi: 10.23822/EurAnnACI.1764-1489.310. Online ahead of print. Eur Ann Allergy Clin Immunol. 2023. PMID: 37671889 Free article. No abstract available.
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid.
Lechner S, Steimbach RR, Wang L, Deline ML, Chang YC, Fromme T, Klingenspor M, Matthias P, Miller AK, Médard G, Kuster B. Lechner S, et al. Nat Commun. 2023 Jun 15;14(1):3548. doi: 10.1038/s41467-023-39151-8. Nat Commun. 2023. PMID: 37322067 Free PMC article.
Lipoic acid is an essential enzyme cofactor in central metabolic pathways. ...Moreover, (R/S)-lipoic acid is an approved drug for the treatment of diabetic neuropathy. ...
Lipoic acid is an essential enzyme cofactor in central metabolic pathways. ...Moreover, (R/S)-lipoic acid is an …
Lipoic acid. Kinetics and pluripotent biological properties and derivatives.
Theodosis-Nobelos P, Papagiouvannis G, Tziona P, Rekka EA. Theodosis-Nobelos P, et al. Mol Biol Rep. 2021 Sep;48(9):6539-6550. doi: 10.1007/s11033-021-06643-z. Epub 2021 Aug 22. Mol Biol Rep. 2021. PMID: 34420148 Review.
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profile of the compound are commented, together with its stability issues. Mechanisms of lipoic acid intervention in the human body …
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profi …
Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy.
Bingham PM, Stuart SD, Zachar Z. Bingham PM, et al. Expert Rev Clin Pharmacol. 2014 Nov;7(6):837-46. doi: 10.1586/17512433.2014.966816. Epub 2014 Oct 4. Expert Rev Clin Pharmacol. 2014. PMID: 25284345 Review.
The lipoic acid (lipoate) coenzyme is unique in all of mammalian metabolism. ...
The lipoic acid (lipoate) coenzyme is unique in all of mammalian metabolism. ...
Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention.
Tripathi AK, Ray AK, Mishra SK, Bishen SM, Mishra H, Khurana A. Tripathi AK, et al. Rev Bras Farmacogn. 2023;33(2):272-287. doi: 10.1007/s43450-023-00370-1. Epub 2023 Feb 7. Rev Bras Farmacogn. 2023. PMID: 36778891 Free PMC article. Review.
Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and animals. ...A healthy human body, on the other hand, can synthesize enough alpha-lipoic acid to scavenge reactive oxygen species and increase endogenous antioxidant …
Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and animals. ...A healthy human body, on t …
alpha-Lipoic Acid Alleviated Fluoride-Induced Hepatocyte Injury via Inhibiting Ferroptosis.
Zhao Y, Liu X, Liang C, Pei T, Guo M, Wang J, Zhang J. Zhao Y, et al. J Agric Food Chem. 2022 Dec 21;70(50):15962-15971. doi: 10.1021/acs.jafc.2c07484. Epub 2022 Dec 2. J Agric Food Chem. 2022. PMID: 36459405
However, the protective effect of alpha-lipoic acid on fluorohepatotoxicity is uncertain. The aim of this study was to investigate the mechanism of ferroptosis in alpha-lipoic acid preventing fluoride-induced hepatotoxicity. Five-week-old ICR mice were …
However, the protective effect of alpha-lipoic acid on fluorohepatotoxicity is uncertain. The aim of this study was to investi …
5,901 results