Lisanti MP - Search Results

1

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.

Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Lee H, et al. Among authors: lisanti mp. Am J Pathol. 2002 Oct;161(4):1357-69. doi: 10.1016/S0002-9440(10)64412-4. Am J Pathol. 2002. PMID: 12368209 Free PMC article.

2

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities.

Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP. Razani B, et al. Among authors: lisanti mp. J Biol Chem. 2002 Mar 8;277(10):8635-47. doi: 10.1074/jbc.M110970200. Epub 2001 Dec 5. J Biol Chem. 2002. PMID: 11739396 Free article.

3

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M, Shirani J, Razani B, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Park DS, et al. Among authors: lisanti mp. Am J Pathol. 2002 Jun;160(6):2207-17. doi: 10.1016/S0002-9440(10)61168-6. Am J Pathol. 2002. PMID: 12057923 Free PMC article.

4

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP. Park DS, et al. Among authors: lisanti mp. Mol Biol Cell. 2002 Oct;13(10):3416-30. doi: 10.1091/mbc.02-05-0071. Mol Biol Cell. 2002. PMID: 12388746 Free PMC article.

5

Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.

Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: lisanti mp. Mol Biol Cell. 2003 Mar;14(3):1027-42. doi: 10.1091/mbc.e02-08-0503. Mol Biol Cell. 2003. PMID: 12631721 Free PMC article.

6

Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli.

Woodman SE, Ashton AW, Schubert W, Lee H, Williams TM, Medina FA, Wyckoff JB, Combs TP, Lisanti MP. Woodman SE, et al. Among authors: lisanti mp. Am J Pathol. 2003 Jun;162(6):2059-68. doi: 10.1016/S0002-9440(10)64337-4. Am J Pathol. 2003. PMID: 12759260 Free PMC article.

7

Caveolin-1 null (-/-) mice show dramatic reductions in life span.

Park DS, Cohen AW, Frank PG, Razani B, Lee H, Williams TM, Chandra M, Shirani J, De Souza AP, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Park DS, et al. Among authors: lisanti mp. Biochemistry. 2003 Dec 30;42(51):15124-31. doi: 10.1021/bi0356348. Biochemistry. 2003. PMID: 14690422

8

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.

Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: lisanti mp. J Biol Chem. 2004 Jun 4;279(23):24745-56. doi: 10.1074/jbc.M402064200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044451 Free article.

9

Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.

Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: lisanti mp. Cell Cycle. 2005 Dec;4(12):1808-16. doi: 10.4161/cc.4.12.2198. Epub 2005 Dec 22. Cell Cycle. 2005. PMID: 16294019

10

Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.

Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: lisanti mp. Am J Pathol. 2006 Jan;168(1):292-309. doi: 10.2353/ajpath.2006.050429. Am J Pathol. 2006. PMID: 16400031 Free PMC article.

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