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Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine.
Williams AA, Ingram WM, Levine S, Resnik J, Kamel CM, Lish JR, Elizalde DI, Janowski SA, Shoker J, Kozlenkov A, González-Maeso J, Gallitano AL. Williams AA, et al. Among authors: lish jr. Neuropsychopharmacology. 2012 Sep;37(10):2285-98. doi: 10.1038/npp.2012.81. Epub 2012 Jun 13. Neuropsychopharmacology. 2012. PMID: 22692564 Free PMC article.
Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3.
Zhao X, Ozols AB, Meyers KT, Campbell J, McBride A, Marballi KK, Maple AM, Raskin C, Mishra A, Noss SM, Beck KL, Khoshaba R, Bhaskara A, Godbole MN, Lish JR, Kang P, Hu C, Palner M, Overgaard A, Knudsen GM, Gallitano AL. Zhao X, et al. Among authors: lish jr. Mol Psychiatry. 2022 Mar;27(3):1599-1610. doi: 10.1038/s41380-021-01390-w. Epub 2022 Jan 10. Mol Psychiatry. 2022. PMID: 35001075 Free PMC article.