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The synthesized transporter K16APoE enabled the therapeutic HAYED peptide to cross the blood-brain barrier and remove excess iron and radicals in the brain, thus easing Alzheimer's disease.
Zou Z, Shen Q, Pang Y, Li X, Chen Y, Wang X, Luo X, Wu Z, Bao Z, Zhang J, Liang J, Kong L, Yan L, Xiong L, Zhu T, Yuan S, Wang M, Cai K, Yao Y, Wu J, Jiang Y, Liu H, Liu J, Zhou Y, Dong Q, Wang W, Zhu K, Li L, Lou Y, Wang H, Li Y, Lin H. Zou Z, et al. Among authors: liu j, liu h. Drug Deliv Transl Res. 2019 Feb;9(1):394-403. doi: 10.1007/s13346-018-0579-4. Drug Deliv Transl Res. 2019. PMID: 30136122
[{SiNDipp}MgNa]2: A Potent Molecular Reducing Agent.
Liu HY, Neale SE, Hill MS, Mahon MF, McMullin CL, Richards E. Liu HY, et al. Organometallics. 2024 Apr 9;43(8):879-888. doi: 10.1021/acs.organomet.4c00076. eCollection 2024 Apr 22. Organometallics. 2024. PMID: 38665773 Free PMC article.
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