Liu X - Search Results

1

Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol.

Liu X, Alexander C, Serrano J, Borg E, Dawson DC. Liu X, et al. J Biol Chem. 2006 Mar 24;281(12):8275-85. doi: 10.1074/jbc.M512458200. Epub 2006 Jan 24. J Biol Chem. 2006. PMID: 16436375 Free article.

2

CFTR: what's it like inside the pore?

Liu X, Smith SS, Dawson DC. Liu X, et al. J Exp Zool A Comp Exp Biol. 2003 Nov 1;300(1):69-75. doi: 10.1002/jez.a.10311. J Exp Zool A Comp Exp Biol. 2003. PMID: 14598388 Review.

3

CFTR: a cysteine at position 338 in TM6 senses a positive electrostatic potential in the pore.

Liu X, Zhang ZR, Fuller MD, Billingsley J, McCarty NA, Dawson DC. Liu X, et al. Biophys J. 2004 Dec;87(6):3826-41. doi: 10.1529/biophysj.104.050534. Epub 2004 Sep 10. Biophys J. 2004. PMID: 15361410 Free PMC article.

4

Determination of the functional unit of the cystic fibrosis transmembrane conductance regulator chloride channel. One polypeptide forms one pore.

Zhang ZR, Cui G, Liu X, Song B, Dawson DC, McCarty NA. Zhang ZR, et al. Among authors: liu x. J Biol Chem. 2005 Jan 7;280(1):458-68. doi: 10.1074/jbc.M409626200. Epub 2004 Oct 25. J Biol Chem. 2005. PMID: 15504728 Free article.

5

CFTR: Ligand exchange between a permeant anion ([Au(CN)2]-) and an engineered cysteine (T338C) blocks the pore.

Serrano JR, Liu X, Borg ER, Alexander CS, Shaw CF 3rd, Dawson DC. Serrano JR, et al. Among authors: liu x. Biophys J. 2006 Sep 1;91(5):1737-48. doi: 10.1529/biophysj.105.078899. Epub 2006 Jun 9. Biophys J. 2006. PMID: 16766608 Free PMC article.

6

Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore.

Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC. Alexander C, et al. Among authors: liu x. Biochemistry. 2009 Oct 27;48(42):10078-88. doi: 10.1021/bi901314c. Biochemistry. 2009. PMID: 19754156 Free PMC article.

7

Cystic fibrosis transmembrane conductance regulator: temperature-dependent cysteine reactivity suggests different stable conformers of the conduction pathway.

Liu X, Dawson DC. Liu X, et al. Biochemistry. 2011 Nov 29;50(47):10311-7. doi: 10.1021/bi201176q. Epub 2011 Nov 4. Biochemistry. 2011. PMID: 22014307 Free PMC article.

8

Thermal instability of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: protection by single suppressor mutations and inhibiting channel activity.

Liu X, O'Donnell N, Landstrom A, Skach WR, Dawson DC. Liu X, et al. Biochemistry. 2012 Jun 26;51(25):5113-24. doi: 10.1021/bi300018e. Epub 2012 Jun 15. Biochemistry. 2012. PMID: 22680785 Free PMC article.

9

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators protect G551D but not ΔF508 CFTR from thermal instability.

Liu X, Dawson DC. Liu X, et al. Biochemistry. 2014 Sep 9;53(35):5613-8. doi: 10.1021/bi501007v. Epub 2014 Aug 22. Biochemistry. 2014. PMID: 25148434 Free PMC article.

10

WNK1 and WNK4 modulate CFTR activity.

Yang CL, Liu X, Paliege A, Zhu X, Bachmann S, Dawson DC, Ellison DH. Yang CL, et al. Among authors: liu x. Biochem Biophys Res Commun. 2007 Feb 16;353(3):535-40. doi: 10.1016/j.bbrc.2006.11.151. Epub 2006 Dec 15. Biochem Biophys Res Commun. 2007. PMID: 17194447

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