METTL3 inhibits BMSC adipogenic differentiation by targeting the JAK1/STAT5/C/EBPβ pathway via an m6A-YTHDF2-dependent manner.
Yao Y, Bi Z, Wu R, Zhao Y, Liu Y, Liu Q, Wang Y, Wang X.
Yao Y, et al. Among authors: liu y, liu q.
FASEB J. 2019 Jun;33(6):7529-7544. doi: 10.1096/fj.201802644R. Epub 2019 Mar 13.
FASEB J. 2019.
PMID: 30865855
Our findings provide novel insights into the underlying molecular mechanisms of m(6)A modification in the regulation of BMSCs differentiating into adipocytes, which may pave a way to develop more effective therapeutic strategies in stem cell regenerative medicine and the treatmen …
Our findings provide novel insights into the underlying molecular mechanisms of m(6)A modification in the regulation of BMSCs differentiatin …