Locke JB - Search Results

1

Genetic environment and stability of cfr in methicillin-resistant Staphylococcus aureus CM05.

Locke JB, Rahawi S, Lamarre J, Mankin AS, Shaw KJ. Locke JB, et al. Antimicrob Agents Chemother. 2012 Jan;56(1):332-40. doi: 10.1128/AAC.05420-11. Epub 2011 Oct 24. Antimicrob Agents Chemother. 2012. PMID: 22024827 Free PMC article.

2

Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).

Locke JB, Hilgers M, Shaw KJ. Locke JB, et al. Antimicrob Agents Chemother. 2009 Dec;53(12):5265-74. doi: 10.1128/AAC.00871-09. Epub 2009 Sep 14. Antimicrob Agents Chemother. 2009. PMID: 19752277 Free PMC article.

3

Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.

Locke JB, Hilgers M, Shaw KJ. Locke JB, et al. Antimicrob Agents Chemother. 2009 Dec;53(12):5275-8. doi: 10.1128/AAC.01032-09. Epub 2009 Oct 5. Antimicrob Agents Chemother. 2009. PMID: 19805557 Free PMC article.

4

Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations.

Locke JB, Finn J, Hilgers M, Morales G, Rahawi S, G C K, Picazo JJ, Im W, Shaw KJ, Stein JL. Locke JB, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5337-43. doi: 10.1128/AAC.00663-10. Epub 2010 Sep 13. Antimicrob Agents Chemother. 2010. PMID: 20837751 Free PMC article.

5

Elevated linezolid resistance in clinical cfr-positive Staphylococcus aureus isolates is associated with co-occurring mutations in ribosomal protein L3.

Locke JB, Morales G, Hilgers M, G C K, Rahawi S, José Picazo J, Shaw KJ, Stein JL. Locke JB, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5352-5. doi: 10.1128/AAC.00714-10. Epub 2010 Sep 13. Antimicrob Agents Chemother. 2010. PMID: 20837755 Free PMC article.

6

Low fitness cost of the multidrug resistance gene cfr.

LaMarre JM, Locke JB, Shaw KJ, Mankin AS. LaMarre JM, et al. Among authors: locke jb. Antimicrob Agents Chemother. 2011 Aug;55(8):3714-9. doi: 10.1128/AAC.00153-11. Epub 2011 Jun 6. Antimicrob Agents Chemother. 2011. PMID: 21646483 Free PMC article.

7

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.

Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J. Teng M, et al. Among authors: locke jb. J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12. J Med Chem. 2013. PMID: 23362938

8

Tedizolid for the management of human infections: in vitro characteristics.

Locke JB, Zurenko GE, Shaw KJ, Bartizal K. Locke JB, et al. Clin Infect Dis. 2014 Jan;58 Suppl 1:S35-42. doi: 10.1093/cid/cit616. Clin Infect Dis. 2014. PMID: 24343830 Review.

9

Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents.

Tari LW, Li X, Trzoss M, Bensen DC, Chen Z, Lam T, Zhang J, Lee SJ, Hough G, Phillipson D, Akers-Rodriguez S, Cunningham ML, Kwan BP, Nelson KJ, Castellano A, Locke JB, Brown-Driver V, Murphy TM, Ong VS, Pillar CM, Shinabarger DL, Nix J, Lightstone FC, Wong SE, Nguyen TB, Shaw KJ, Finn J. Tari LW, et al. Among authors: locke jb. PLoS One. 2013 Dec 26;8(12):e84409. doi: 10.1371/journal.pone.0084409. eCollection 2013. PLoS One. 2013. PMID: 24386374 Free PMC article.

10

Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center.

Locke JB, Zuill DE, Scharn CR, Deane J, Sahm DF, Goering RV, Jenkins SG, Shaw KJ. Locke JB, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6949-52. doi: 10.1128/AAC.03380-14. Epub 2014 Aug 18. Antimicrob Agents Chemother. 2014. PMID: 25136008 Free PMC article.

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