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Myc-induced T cell leukemia in transgenic zebrafish.
Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. Langenau DM, et al. Among authors: look at. Science. 2003 Feb 7;299(5608):887-90. doi: 10.1126/science.1080280. Science. 2003. PMID: 12574629
Activating Notch1 mutations in mouse models of T-ALL.
O'Neil J, Calvo J, McKenna K, Krishnamoorthy V, Aster JC, Bassing CH, Alt FW, Kelliher M, Look AT. O'Neil J, et al. Among authors: look at. Blood. 2006 Jan 15;107(2):781-5. doi: 10.1182/blood-2005-06-2553. Epub 2005 Sep 15. Blood. 2006. PMID: 16166587 Free PMC article.
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Palomero T, Lim WK, Odom DT, Sulis ML, Real PJ, Margolin A, Barnes KC, O'Neil J, Neuberg D, Weng AP, Aster JC, Sigaux F, Soulier J, Look AT, Young RA, Califano A, Ferrando AA. Palomero T, et al. Among authors: look at. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18261-6. doi: 10.1073/pnas.0606108103. Epub 2006 Nov 17. Proc Natl Acad Sci U S A. 2006. PMID: 17114293 Free PMC article.
NOTCH1-induced T-cell leukemia in transgenic zebrafish.
Chen J, Jette C, Kanki JP, Aster JC, Look AT, Griffin JD. Chen J, et al. Among authors: look at. Leukemia. 2007 Mar;21(3):462-71. doi: 10.1038/sj.leu.2404546. Epub 2007 Jan 25. Leukemia. 2007. PMID: 17252014
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.
Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, DePinho RA. Maser RS, et al. Among authors: look at. Nature. 2007 Jun 21;447(7147):966-71. doi: 10.1038/nature05886. Epub 2007 May 21. Nature. 2007. PMID: 17515920 Free PMC article.
Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development.
Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT. Shin J, et al. Among authors: look at. Dis Model Mech. 2012 Nov;5(6):881-94. doi: 10.1242/dmm.009779. Epub 2012 Jul 5. Dis Model Mech. 2012. PMID: 22773753 Free PMC article.
438 results