Loomes KM - Search Results

1

Survival of an islet β-cell in type-2 diabetes: curbing the effects of amyloid cytotoxicity.

Loomes KM. Loomes KM. Islets. 2011 Jan-Feb;3(1):38-9. doi: 10.4161/isl.3.1.14258. Epub 2011 Jan 1. Islets. 2011. PMID: 21266844 Review.

2

Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice.

Aitken JF, Loomes KM, Scott DW, Reddy S, Phillips AR, Prijic G, Fernando C, Zhang S, Broadhurst R, L'Huillier P, Cooper GJ. Aitken JF, et al. Among authors: loomes km. Diabetes. 2010 Jan;59(1):161-71. doi: 10.2337/db09-0548. Epub 2009 Sep 30. Diabetes. 2010. PMID: 19794060 Free PMC article.

3

Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice.

Aitken JF, Loomes KM, Riba-Garcia I, Unwin RD, Prijic G, Phillips AS, Phillips ARJ, Wu D, Poppitt SD, Ding K, Barran PE, Dowsey AW, Cooper GJS. Aitken JF, et al. Among authors: loomes km. Biochem Biophys Res Commun. 2017 Jan 22;482(4):625-631. doi: 10.1016/j.bbrc.2016.11.083. Epub 2016 Nov 16. Biochem Biophys Res Commun. 2017. PMID: 27865831

4

Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

Aitken JF, Loomes KM, Konarkowska B, Cooper GJ. Aitken JF, et al. Among authors: loomes km. Biochem J. 2003 Sep 15;374(Pt 3):779-84. doi: 10.1042/BJ20030422. Biochem J. 2003. PMID: 12812521 Free PMC article.

5

The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes.

Chien V, Aitken JF, Zhang S, Buchanan CM, Hickey A, Brittain T, Cooper GJ, Loomes KM. Chien V, et al. Among authors: loomes km. Biochem J. 2010 Nov 15;432(1):113-21. doi: 10.1042/BJ20100434. Biochem J. 2010. PMID: 20735358

6

The diabetic rat kidney mediates inosituria and selective urinary partitioning of D-chiro-inositol.

Chang HH, Choong B, Phillips AR, Loomes KM. Chang HH, et al. Among authors: loomes km. Exp Biol Med (Maywood). 2015 Jan;240(1):8-14. doi: 10.1177/1535370214543064. Epub 2014 Jul 24. Exp Biol Med (Maywood). 2015. PMID: 25060739 Free PMC article.

7

Renal depletion of myo-inositol is associated with its increased degradation in animal models of metabolic disease.

Chang HH, Chao HN, Walker CS, Choong SY, Phillips A, Loomes KM. Chang HH, et al. Among authors: loomes km. Am J Physiol Renal Physiol. 2015 Nov 1;309(9):F755-63. doi: 10.1152/ajprenal.00164.2015. Epub 2015 Aug 26. Am J Physiol Renal Physiol. 2015. PMID: 26311112 Free article.

8

Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes.

Bailey RJ, Walker CS, Ferner AH, Loomes KM, Prijic G, Halim A, Whiting L, Phillips AR, Hay DL. Bailey RJ, et al. Among authors: loomes km. Br J Pharmacol. 2012 May;166(1):151-67. doi: 10.1111/j.1476-5381.2011.01717.x. Br J Pharmacol. 2012. PMID: 22014233 Free PMC article.

9

D-chiro-inositol attenuates epinephrine-stimulated hepatic glucose output in the isolated perfused liver independently of insulin.

Whiting L, Danaher RN, Ruggiero K, Lee CC, Chaussade C, Mulvey T, Phillips A, Loomes KM. Whiting L, et al. Among authors: loomes km. Horm Metab Res. 2013 May;45(5):394-7. doi: 10.1055/s-0032-1330016. Epub 2012 Dec 7. Horm Metab Res. 2013. PMID: 23225249

10

Isolated perfused rat kidney: a technical update.

Chang HH, Choong B, Phillips A, Loomes KM. Chang HH, et al. Among authors: loomes km. Exp Anim. 2013;62(1):19-23. doi: 10.1538/expanim.62.19. Exp Anim. 2013. PMID: 23357942 Free article.

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