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Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma.
Allen-Petersen BL, Risom T, Feng Z, Wang Z, Jenny ZP, Thoma MC, Pelz KR, Morton JP, Sansom OJ, Lopez CD, Sheppard B, Christensen DJ, Ohlmeyer M, Narla G, Sears RC. Allen-Petersen BL, et al. Among authors: lopez cd. Cancer Res. 2019 Jan 1;79(1):209-219. doi: 10.1158/0008-5472.CAN-18-0717. Epub 2018 Nov 2. Cancer Res. 2019. PMID: 30389701 Free PMC article.
ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival.
Van Hook K, Wang Z, Chen D, Nold C, Zhu Z, Anur P, Lee HJ, Yu Z, Sheppard B, Dai MS, Sears R, Spellman P, Lopez CD. Van Hook K, et al. Among authors: lopez cd. Biochem Biophys Res Commun. 2017 Jan 22;482(4):1271-1277. doi: 10.1016/j.bbrc.2016.12.027. Epub 2016 Dec 8. Biochem Biophys Res Commun. 2017. PMID: 27939881 Free PMC article.
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.
Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH. Gast CE, et al. Among authors: lopez cd. Sci Adv. 2018 Sep 12;4(9):eaat7828. doi: 10.1126/sciadv.aat7828. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30214939 Free PMC article.
Tumor-Infiltrating Leukocyte Phenotypes Distinguish Outcomes in Related Patients With Pancreatic Adenocarcinoma.
Link JM, Liudahl SM, Betts CB, Sivagnanam S, Leis KR, McDonnell M, Pelz CR, Johnson B, Hamman KJ, Keith D, Sampson JE, Morgan TK, Lopez CD, Coussens LM, Sears RC. Link JM, et al. Among authors: lopez cd. JCO Precis Oncol. 2021 Feb 5;5:PO.20.00287. doi: 10.1200/PO.20.00287. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34036232 Free PMC article. No abstract available.
Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors.
Dietz MS, Sutton TL, Walker BS, Gast CE, Zarour L, Sengupta SK, Swain JR, Eng J, Parappilly M, Limbach K, Sattler A, Burlingame E, Chin Y, Gower A, Mira JLM, Sapre A, Chiu YJ, Clayburgh DR, Pommier SJ, Cetnar JP, Fischer JM, Jaboin JJ, Pommier RF, Sheppard BC, Tsikitis VL, Skalet AH, Mayo SC, Lopez CD, Gray JW, Mills GB, Mitri Z, Chang YH, Chin K, Wong MH. Dietz MS, et al. Among authors: lopez cd. Sci Rep. 2021 Jul 1;11(1):13630. doi: 10.1038/s41598-021-93053-7. Sci Rep. 2021. PMID: 34211050 Free PMC article.
156 results