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The Use of Global Sensitivity Analysis to Assess the Oral Absorption of Weakly Basic Compounds: A Case Example of Dipyridamole.
Pharm Res. 2024 Mar 27. doi: 10.1007/s11095-024-03688-0. Online ahead of print.
Pharm Res. 2024.
PMID: 38538971
Biorelevant subcutaneous in vitro test predicts the release of human and fast acting insulin formulations.
Schöner TA, Vogel V, Venczel M, Knoth K, Kamm W, Paehler T, Louit G, Terán IT, Mundinger P, Marker A, Loos P, Hittinger M, Lehr CM.
Schöner TA, et al. Among authors: louit g.
Int J Pharm. 2024 Apr 25;655:123995. doi: 10.1016/j.ijpharm.2024.123995. Epub 2024 Mar 14.
Int J Pharm. 2024.
PMID: 38490402
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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, Gobeau N, Wittlin S, Uhlemann AC, Price RN, Wirjanata G, Noviyanti R, Tumwebaze P, Cooper RA, Rosenthal PJ, Sanz LM, Gamo FJ, Joseph J, Singh S, Bashyam S, Augereau JM, Giraud E, Bozec T, Vermat T, Tuffal G, Guillon JM, Menegotto J, Sallé L, Louit G, Cabanis MJ, Nicolas MF, Doubovetzky M, Merino R, Bessila N, Angulo-Barturen I, Baud D, Bebrevska L, Escudié F, Niles JC, Blasco B, Campbell S, Courtemanche G, Fraisse L, Pellet A, Fidock DA, Leroy D.
Murithi JM, et al. Among authors: louit g.
Sci Transl Med. 2021 Jul 21;13(603):eabg6013. doi: 10.1126/scitranslmed.abg6013.
Sci Transl Med. 2021.
PMID: 34290058
Free PMC article.
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IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Ahmad A, Pepin X, Aarons L, Wang Y, Darwich AS, Wood JM, Tannergren C, Karlsson E, Patterson C, Thörn H, Ruston L, Mattinson A, Carlert S, Berg S, Murphy D, Engman H, Laru J, Barker R, Flanagan T, Abrahamsson B, Budhdeo S, Franek F, Moir A, Hanisch G, Pathak SM, Turner D, Jamei M, Brown J, Good D, Vaidhyanathan S, Jackson C, Nicolas O, Beilles S, Nguefack JF, Louit G, Henrion L, Ollier C, Boulu L, Xu C, Heimbach T, Ren X, Lin W, Nguyen-Trung AT, Zhang J, He H, Wu F, Bolger MB, Mullin JM, van Osdol B, Szeto K, Korjamo T, Pappinen S, Tuunainen J, Zhu W, Xia B, Daublain P, Wong S, Varma MVS, Modi S, Schäfer KJ, Schmid K, Lloyd R, Patel A, Tistaert C, Bevernage J, Nguyen MA, Lindley D, Carr R, Rostami-Hodjegan A.
Ahmad A, et al. Among authors: louit g.
Eur J Pharm Biopharm. 2020 Nov;156:50-63. doi: 10.1016/j.ejpb.2020.08.006. Epub 2020 Aug 14.
Eur J Pharm Biopharm. 2020.
PMID: 32805361
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Y-shaped mPEG-PLA cabazitaxel conjugates: well-controlled synthesis by organocatalytic approach and self-assembly into interface drug-loaded core-corona nanoparticles.
Bensaid F, Thillaye du Boullay O, Amgoune A, Pradel C, Harivardhan Reddy L, Didier E, Sablé S, Louit G, Bazile D, Bourissou D.
Bensaid F, et al. Among authors: louit g.
Biomacromolecules. 2013 Apr 8;14(4):1189-98. doi: 10.1021/bm400161g. Epub 2013 Mar 5.
Biomacromolecules. 2013.
PMID: 23432356
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Determination of hydroxyl rate constants by a high-throughput fluorimetric assay: towards a unified reactivity scale for antioxidants.
Louit G, Hanedanian M, Taran F, Coffigny H, Renault JP, Pin S.
Louit G, et al.
Analyst. 2009 Feb;134(2):250-5. doi: 10.1039/b813871k. Epub 2008 Nov 19.
Analyst. 2009.
PMID: 19173045
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