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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 1
1978 3
1979 2
1980 16
1981 18
1982 19
1983 37
1984 29
1985 33
1986 44
1987 55
1988 98
1989 138
1990 216
1991 239
1992 223
1993 242
1994 243
1995 306
1996 252
1997 270
1998 298
1999 331
2000 288
2001 441
2002 410
2003 471
2004 454
2005 506
2006 514
2007 534
2008 681
2009 578
2010 611
2011 630
2012 556
2013 599
2014 581
2015 573
2016 551
2017 469
2018 441
2019 442
2020 406
2021 338
2022 308
2023 278
2024 85

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13,591 results

Results by year

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Page 1
HMG-CoA reductase inhibitors.
Endo A, Hasumi K. Endo A, et al. Nat Prod Rep. 1993 Dec;10(6):541-50. doi: 10.1039/np9931000541. Nat Prod Rep. 1993. PMID: 8121646 Review. No abstract available.
Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models.
Kansal V, Burnham AJ, Kinney BLC, Saba NF, Paulos C, Lesinski GB, Buchwald ZS, Schmitt NC. Kansal V, et al. J Immunother Cancer. 2023 Jan;11(1):e005940. doi: 10.1136/jitc-2022-005940. J Immunother Cancer. 2023. PMID: 36650022 Free PMC article.
RESULTS: Using an ex vivo coculture assay of murine cancer cells and tumor infiltrating lymphocytes, we discovered that all seven statin drugs inhibited tumor cell proliferation. Simvastatin and lovastatin also enhanced T-cell killing of tumor cells. In mice, daily oral si …
RESULTS: Using an ex vivo coculture assay of murine cancer cells and tumor infiltrating lymphocytes, we discovered that all seven statin dru …
Lovastatin for hypercholesterolemia.
Zeller FP, Uvodich KC. Zeller FP, et al. Drug Intell Clin Pharm. 1988 Jul-Aug;22(7-8):542-5. doi: 10.1177/106002808802200703. Drug Intell Clin Pharm. 1988. PMID: 3046888 Review.
One percent of lovastatin patients have discontinued therapy because of intolerable side effects. ...Although the drug should be added to hospital formularies, long-term safety experience and competition from other HMG-CoA reductase inhibitors will determine lovastatin …
One percent of lovastatin patients have discontinued therapy because of intolerable side effects. ...Although the drug should be adde …
Effects of Lovastatin on Brain Cancer Cells.
Amadasu E, Kang R, Usmani A, Borlongan CV. Amadasu E, et al. Cell Transplant. 2022 Jan-Dec;31:9636897221102903. doi: 10.1177/09636897221102903. Cell Transplant. 2022. PMID: 35670207 Free PMC article. Review.
An emerging approach to targeting CSCs in brain tumors is through repurposing the lipid-lowering medication, lovastatin. Lovastatin is a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that impacts the mevalonate pathway. The inhibition of interm …
An emerging approach to targeting CSCs in brain tumors is through repurposing the lipid-lowering medication, lovastatin. Lovastati …
Compactin-a review.
Chakravarti R, Sahai V. Chakravarti R, et al. Appl Microbiol Biotechnol. 2004 Jun;64(5):618-24. doi: 10.1007/s00253-003-1553-7. Epub 2004 Mar 19. Appl Microbiol Biotechnol. 2004. PMID: 15034683 Review.
Therapeutic metabolites.
Masurekar PS. Masurekar PS. Biotechnology. 1992;21:241-301. doi: 10.1016/b978-0-7506-9115-4.50016-4. Biotechnology. 1992. PMID: 1576481 Review. No abstract available.
[Simvastatin].
Burgmer U, Mohr K. Burgmer U, et al. Dtsch Med Wochenschr. 1996 Jun 7;121(23):769-70. doi: 10.1055/s-0029-1234183. Dtsch Med Wochenschr. 1996. PMID: 8646995 German. No abstract available.
An overview of the bioactivity of monacolin K / lovastatin.
Xiong Z, Cao X, Wen Q, Chen Z, Cheng Z, Huang X, Zhang Y, Long C, Zhang Y, Huang Z. Xiong Z, et al. Food Chem Toxicol. 2019 Sep;131:110585. doi: 10.1016/j.fct.2019.110585. Epub 2019 Jun 15. Food Chem Toxicol. 2019. PMID: 31207306 Review.
Simvastatin.
Yeatman E. Yeatman E. Aust Nurses J. 1991 Jul;21(1):29-30. Aust Nurses J. 1991. PMID: 1929970 No abstract available.
An overview on the biosynthesis and metabolic regulation of monacolin K/lovastatin.
Zhang Y, Chen Z, Wen Q, Xiong Z, Cao X, Zheng Z, Zhang Y, Huang Z. Zhang Y, et al. Food Funct. 2020 Jul 22;11(7):5738-5748. doi: 10.1039/d0fo00691b. Food Funct. 2020. PMID: 32555902 Review.
Lovastatin's biosynthetic pathway and gene cluster composition have been studied in depth in Aspergillus terreus. Evidence shows that the MK biosynthetic pathway and gene cluster in Monascus sp. are similar to those of lovastatin in A. terreus. Currently, res …
Lovastatin's biosynthetic pathway and gene cluster composition have been studied in depth in Aspergillus terreus. Evidence sho …
13,591 results
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