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Immunoreactivity to ubiquitin-protein conjugates is present early in the disease process in the brains of scrapie-infected mice.
Lowe J, Fergusson J, Kenward N, Laszlo L, Landon M, Farquhar C, Brown J, Hope J, Mayer RJ. Lowe J, et al. J Pathol. 1992 Oct;168(2):169-77. doi: 10.1002/path.1711680204. J Pathol. 1992. PMID: 1334140
In both models, the extent of immunoreactive changes increased as the disease progressed and terminal infection was as described earlier by us (Lowe et al., J. Pathol 1990; 162: 61-66). The patterns of development of these features were distinctive in two ways: prog …
In both models, the extent of immunoreactive changes increased as the disease progressed and terminal infection was as described earlier by …
Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease.
Lowe J, Blanchard A, Morrell K, Lennox G, Reynolds L, Billett M, Landon M, Mayer RJ. Lowe J, et al. J Pathol. 1988 May;155(1):9-15. doi: 10.1002/path.1711550105. J Pathol. 1988. PMID: 2837558
2,702 results