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Platelets in lymph vessel development and integrity.
Watson SP, Lowe K, Finney BA. Watson SP, et al. Among authors: lowe k. Adv Anat Embryol Cell Biol. 2014;214:93-105. doi: 10.1007/978-3-7091-1646-3_8. Adv Anat Embryol Cell Biol. 2014. PMID: 24276889 Review.
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.
Finney BA, Schweighoffer E, Navarro-Núñez L, Bénézech C, Barone F, Hughes CE, Langan SA, Lowe KL, Pollitt AY, Mourao-Sa D, Sheardown S, Nash GB, Smithers N, Reis e Sousa C, Tybulewicz VL, Watson SP. Finney BA, et al. Blood. 2012 Feb 16;119(7):1747-56. doi: 10.1182/blood-2011-09-380709. Epub 2011 Dec 20. Blood. 2012. PMID: 22186994 Free PMC article.
CLEC-2 is required for development and maintenance of lymph nodes.
Bénézech C, Nayar S, Finney BA, Withers DR, Lowe K, Desanti GE, Marriott CL, Watson SP, Caamaño JH, Buckley CD, Barone F. Bénézech C, et al. Among authors: lowe k. Blood. 2014 May 15;123(20):3200-7. doi: 10.1182/blood-2013-03-489286. Epub 2014 Feb 14. Blood. 2014. PMID: 24532804 Free PMC article.
Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.
Lax S, Rayes J, Wichaiyo S, Haining EJ, Lowe K, Grygielska B, Laloo R, Flodby P, Borok Z, Crandall ED, Thickett DR, Watson SP. Lax S, et al. Among authors: lowe k. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1016-L1029. doi: 10.1152/ajplung.00023.2017. Epub 2017 Aug 24. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28839100 Free PMC article.
Lymphatic blood filling in CLEC-2-deficient mouse models.
Haining EJ, Lowe KL, Wichaiyo S, Kataru RP, Nagy Z, Kavanagh DP, Lax S, Di Y, Nieswandt B, Ho-Tin-Noé B, Mehrara BJ, Senis YA, Rayes J, Watson SP. Haining EJ, et al. Platelets. 2021 Apr 3;32(3):352-367. doi: 10.1080/09537104.2020.1734784. Epub 2020 Mar 4. Platelets. 2021. PMID: 32129691 Free PMC article.
587 results