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Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.
Taldone T, Kang Y, Patel HJ, Patel MR, Patel PD, Rodina A, Patel Y, Gozman A, Maharaj R, Clement CC, Lu A, Young JC, Chiosis G. Taldone T, et al. Among authors: lu a. J Med Chem. 2014 Feb 27;57(4):1208-24. doi: 10.1021/jm401552y. Epub 2014 Feb 18. J Med Chem. 2014. PMID: 24548239 Free PMC article.
The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.
Vajjhala PR, Lu A, Brown DL, Pang SW, Sagulenko V, Sester DP, Cridland SO, Hill JM, Schroder K, Stow JL, Wu H, Stacey KJ. Vajjhala PR, et al. Among authors: lu a. J Biol Chem. 2015 Dec 4;290(49):29217-30. doi: 10.1074/jbc.M115.687731. Epub 2015 Oct 14. J Biol Chem. 2015. PMID: 26468282 Free PMC article.
Structural mechanisms of inflammasome assembly.
Lu A, Wu H. Lu A, et al. FEBS J. 2015 Feb;282(3):435-44. doi: 10.1111/febs.13133. Epub 2014 Nov 21. FEBS J. 2015. PMID: 25354325 Free PMC article. Review.
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Leung W, Shaffer CD, Reed LK, Smith ST, Barshop W, Dirkes W, Dothager M, Lee P, Wong J, Xiong D, Yuan H, Bedard JE, Machone JF, Patterson SD, Price AL, Turner BA, Robic S, Luippold EK, McCartha SR, Walji TA, Walker CA, Saville K, Abrams MK, Armstrong AR, Armstrong W, Bailey RJ, Barberi CR, Beck LR, Blaker AL, Blunden CE, Brand JP, Brock EJ, Brooks DW, Brown M, Butzler SC, Clark EM, Clark NB, Collins AA, Cotteleer RJ, Cullimore PR, Dawson SG, Docking CT, Dorsett SL, Dougherty GA, Downey KA, Drake AP, Earl EK, Floyd TG, Forsyth JD, Foust JD, Franchi SL, Geary JF, Hanson CK, Harding TS, Harris CB, Heckman JM, Holderness HL, Howey NA, Jacobs DA, Jewell ES, Kaisler M, Karaska EA, Kehoe JL, Koaches HC, Koehler J, Koenig D, Kujawski AJ, Kus JE, Lammers JA, Leads RR, Leatherman EC, Lippert RN, Messenger GS, Morrow AT, Newcomb V, Plasman HJ, Potocny SJ, Powers MK, Reem RM, Rennhack JP, Reynolds KR, Reynolds LA, Rhee DK, Rivard AB, Ronk AJ, Rooney MB, Rubin LS, Salbert LR, Saluja RK, Schauder T, Schneiter AR, Schulz RW, Smith KE, Spencer S, Swanson BR, Tache MA, Tewilliager AA, Tilot AK, VanEck E, Villerot MM, Vylonis MB, Watson DT, Wurzler JA, Wysocki LM, Yalamanchili M, Zaborowicz MA, Eme… See abstract for full author list ➔ Leung W, et al. Among authors: lu a. G3 (Bethesda). 2015 Mar 4;5(5):719-40. doi: 10.1534/g3.114.015966. G3 (Bethesda). 2015. PMID: 25740935 Free PMC article.
Instant Hydrogelation Inspired by Inflammasomes.
Wang H, Feng Z, Lu A, Jiang Y, Wu H, Xu B. Wang H, et al. Among authors: lu a. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7579-7583. doi: 10.1002/anie.201702783. Epub 2017 May 24. Angew Chem Int Ed Engl. 2017. PMID: 28481474 Free PMC article.
3,220 results