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PD-1 marks dysfunctional regulatory T cells in malignant gliomas.
Lowther DE, Goods BA, Lucca LE, Lerner BA, Raddassi K, van Dijk D, Hernandez AL, Duan X, Gunel M, Coric V, Krishnaswamy S, Love JC, Hafler DA. Lowther DE, et al. Among authors: lucca le. JCI Insight. 2016 Apr 21;1(5):e85935. doi: 10.1172/jci.insight.85935. JCI Insight. 2016. PMID: 27182555 Free PMC article.
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation.
Pichler AC, Carrié N, Cuisinier M, Ghazali S, Voisin A, Axisa PP, Tosolini M, Mazzotti C, Golec DP, Maheo S, do Souto L, Ekren R, Blanquart E, Lemaitre L, Feliu V, Joubert MV, Cannons JL, Guillerey C, Avet-Loiseau H, Watts TH, Salomon BL, Joffre O, Grinberg-Bleyer Y, Schwartzberg PL, Lucca LE, Martinet L. Pichler AC, et al. Among authors: lucca le. Immunity. 2023 Jul 11;56(7):1631-1648.e10. doi: 10.1016/j.immuni.2023.06.007. Epub 2023 Jun 30. Immunity. 2023. PMID: 37392737 Free PMC article.
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