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Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2.
Prabhakar S, Beauchamp RL, Cheah PS, Yoshinaga A, Haidar EA, Lule S, Mani G, Maalouf K, Stemmer-Rachamimov A, Jung DH, Welling DB, Giovannini M, Plotkin SR, Maguire CA, Ramesh V, Breakefield XO. Prabhakar S, et al. Among authors: lule s. Mol Ther Methods Clin Dev. 2022 Jun 22;26:169-180. doi: 10.1016/j.omtm.2022.06.012. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 35846573 Free PMC article.
A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles.
Sekerdag E, Lüle S, Bozdağ Pehlivan S, Öztürk N, Kara A, Kaffashi A, Vural I, Işıkay I, Yavuz B, Oguz KK, Söylemezoğlu F, Gürsoy-Özdemir Y, Mut M. Sekerdag E, et al. Among authors: lule s. J Control Release. 2017 Sep 10;261:187-198. doi: 10.1016/j.jconrel.2017.06.032. Epub 2017 Jul 3. J Control Release. 2017. PMID: 28684169
Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice.
Lule S, Wu L, Sarro-Schwartz A, Edmiston WJ 3rd, Izzy S, Songtachalert T, Ahn SH, Fernandes ND, Jin G, Chung JY, Balachandran S, Lo EH, Kaplan D, Degterev A, Whalen MJ. Lule S, et al. J Cereb Blood Flow Metab. 2021 Jul;41(7):1623-1633. doi: 10.1177/0271678X20973609. Epub 2020 Nov 19. J Cereb Blood Flow Metab. 2021. PMID: 33210566 Free PMC article.
Both mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 and phosphatidylinositide-3-OH kinase (PI3K)/Akt pathways regulate activation of E-twenty-six (ETS)-like transcription factor 1 (Elk-1) in U138 glioblastoma cells.
Mut M, Lule S, Demir O, Kurnaz IA, Vural I. Mut M, et al. Among authors: lule s. Int J Biochem Cell Biol. 2012 Feb;44(2):302-10. doi: 10.1016/j.biocel.2011.10.025. Epub 2011 Nov 7. Int J Biochem Cell Biol. 2012. PMID: 22085529
Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection.
Yemisci M, Caban S, Gursoy-Ozdemir Y, Lule S, Novoa-Carballal R, Riguera R, Fernandez-Megia E, Andrieux K, Couvreur P, Capan Y, Dalkara T. Yemisci M, et al. Among authors: lule s. J Cereb Blood Flow Metab. 2015 Mar;35(3):469-75. doi: 10.1038/jcbfm.2014.220. Epub 2014 Dec 10. J Cereb Blood Flow Metab. 2015. PMID: 25492116 Free PMC article.
72 results