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Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Kool J, Uren AG, Martins CP, Sie D, de Ridder J, Turner G, van Uitert M, Matentzoglu K, Lagcher W, Krimpenfort P, Gadiot J, Pritchard C, Lenz J, Lund AH, Jonkers J, Rogers J, Adams DJ, Wessels L, Berns A, van Lohuizen M. Kool J, et al. Among authors: lund ah. Cancer Res. 2010 Jan 15;70(2):520-31. doi: 10.1158/0008-5472.CAN-09-2736. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068150 Free PMC article.
RUNX: a trilogy of cancer genes.
Lund AH, van Lohuizen M. Lund AH, et al. Cancer Cell. 2002 Apr;1(3):213-5. doi: 10.1016/s1535-6108(02)00049-1. Cancer Cell. 2002. PMID: 12086855 Free article. Review.
Epigenetics and cancer.
Lund AH, van Lohuizen M. Lund AH, et al. Genes Dev. 2004 Oct 1;18(19):2315-35. doi: 10.1101/gad.1232504. Genes Dev. 2004. PMID: 15466484 Free article. Review.
Polycomb complexes and silencing mechanisms.
Lund AH, van Lohuizen M. Lund AH, et al. Curr Opin Cell Biol. 2004 Jun;16(3):239-46. doi: 10.1016/j.ceb.2004.03.010. Curr Opin Cell Biol. 2004. PMID: 15145347 Review.
Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.
Muyrers-Chen I, Hernández-Muñoz I, Lund AH, Valk-Lingbeek ME, van der Stoop P, Boutsma E, Tolhuis B, Bruggeman SW, Taghavi P, Verhoeven E, Hulsman D, Noback S, Tanger E, Theunissen H, van Lohuizen M. Muyrers-Chen I, et al. Among authors: lund ah. Cold Spring Harb Symp Quant Biol. 2004;69:319-26. doi: 10.1101/sqb.2004.69.319. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117664 Review. No abstract available.
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.
Hernández-Muñoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M. Hernández-Muñoz I, et al. Among authors: lund ah. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7635-40. doi: 10.1073/pnas.0408918102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897469 Free PMC article.
An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity.
Wynendaele J, Böhnke A, Leucci E, Nielsen SJ, Lambertz I, Hammer S, Sbrzesny N, Kubitza D, Wolf A, Gradhand E, Balschun K, Braicu I, Sehouli J, Darb-Esfahani S, Denkert C, Thomssen C, Hauptmann S, Lund A, Marine JC, Bartel F. Wynendaele J, et al. Cancer Res. 2010 Dec 1;70(23):9641-9. doi: 10.1158/0008-5472.CAN-10-0527. Epub 2010 Nov 16. Cancer Res. 2010. PMID: 21084273
107 results