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Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation.
Kärkkäinen AM, Kotimaa A, Huusko J, Kholova I, Heinonen SE, Stefanska A, Dijkstra MH, Purhonen H, Hämäläinen E, Mäkinen PI, Turunen MP, Ylä-Herttuala S. Kärkkäinen AM, et al. Among authors: makinen pi. Blood. 2009 Apr 30;113(18):4468-75. doi: 10.1182/blood-2008-07-171108. Epub 2008 Dec 10. Blood. 2009. PMID: 19074006 Free article.
The absence of macrophage Nrf2 promotes early atherogenesis.
Ruotsalainen AK, Inkala M, Partanen ME, Lappalainen JP, Kansanen E, Mäkinen PI, Heinonen SE, Laitinen HM, Heikkilä J, Vatanen T, Hörkkö S, Yamamoto M, Ylä-Herttuala S, Jauhiainen M, Levonen AL. Ruotsalainen AK, et al. Among authors: makinen pi. Cardiovasc Res. 2013 Apr 1;98(1):107-15. doi: 10.1093/cvr/cvt008. Epub 2013 Jan 22. Cardiovasc Res. 2013. PMID: 23341579
Enhanced polyamine catabolism disturbs hematopoietic lineage commitment and leads to a myeloproliferative disease in mice overexpressing spermidine/spermine N¹-acetyltransferase.
Pirnes-Karhu S, Mäntymaa P, Sironen R, Mäkinen PI, Wojciechowski S, Juutinen S, Koistinaho J, Hörkkö S, Jantunen E, Alhonen L, Uimari A. Pirnes-Karhu S, et al. Among authors: makinen pi. Amino Acids. 2014 Mar;46(3):689-700. doi: 10.1007/s00726-013-1546-5. Epub 2013 Jul 9. Amino Acids. 2014. PMID: 23836421
Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study.
Babu M, Durga Devi T, Mäkinen P, Kaikkonen M, Lesch HP, Junttila S, Laiho A, Ghimire B, Gyenesei A, Ylä-Herttuala S. Babu M, et al. Circ Res. 2015 Jul 17;117(3):289-99. doi: 10.1161/CIRCRESAHA.115.306424. Epub 2015 Jun 17. Circ Res. 2015. PMID: 26085133
56 results