Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1999 1
2000 1
2001 2
2002 1
2003 4
2004 3
2005 7
2006 6
2007 2
2008 7
2009 8
2010 6
2011 7
2012 7
2013 4
2014 6
2015 10
2016 8
2017 9
2018 13
2019 11
2020 11
2021 8
2022 12
2023 9
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

148 results

Results by year

Filters applied: . Clear all
Page 1
SUMOylated MAFB promotes colorectal cancer tumorigenesis.
Yang LS, Zhang XJ, Xie YY, Sun XJ, Zhao R, Huang QH. Yang LS, et al. Oncotarget. 2016 Dec 13;7(50):83488-83501. doi: 10.18632/oncotarget.13129. Oncotarget. 2016. PMID: 27829226 Free PMC article.
The transcription factor, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB), promotes tumorigenesis in some cancers. In this study, we found that MAFB levels were increased in clinical colorectal cancer (CRC) samples, and higher exp …
The transcription factor, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB), promotes tumorigenesis in some ca …
MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop.
Chen Y, Wang T, Huang M, Liu Q, Hu C, Wang B, Han D, Chen C, Zhang J, Li Z, Liu C, Lei W, Chang Y, Wu M, Xiang D, Chen Y, Wang R, Huang W, Lei Z, Chu X. Chen Y, et al. Cancer Res. 2020 Jun 15;80(12):2472-2483. doi: 10.1158/0008-5472.CAN-19-1764. Epub 2020 Mar 31. Cancer Res. 2020. PMID: 32234710
Sox9 in turn activated MAFB expression via direct recognition of its sequence binding enrichment motif on the MAFB locus, thereby forming a positive feedback regulatory loop. ...Taken together, these findings reveal a MAFB-Sox9 reciprocal regulatory axis driv …
Sox9 in turn activated MAFB expression via direct recognition of its sequence binding enrichment motif on the MAFB locus, ther …
In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis.
Liu W, Zhou X, Yao Q, Chen C, Zhang Q, Ding K, Li L, Zeng Z. Liu W, et al. J Clin Invest. 2023 Apr 17;133(8):e157937. doi: 10.1172/JCI157937. J Clin Invest. 2023. PMID: 36821387 Free PMC article.
Using intravital microscopy, we observed a failure of tumor control by KCs at the late stage of liver metastasis due to KC loss preferentially in the tumor core and periphery, resulting in inaccessibility of these highly phagocytic macrophages to cancer cells. Simultaneous …
Using intravital microscopy, we observed a failure of tumor control by KCs at the late stage of liver metastasis due to KC loss preferential …
MafB silencing in macrophages does not influence the initiation and growth of lung cancer induced by urethane.
Nemoto T, Shibata Y, Inoue S, Igarashi A, Tokairin Y, Yamauchi K, Kimura T, Sato M, Sato K, Nakano H, Abe S, Nishiwaki M, Kobayashi M, Yang S, Minegishi Y, Furuyama K, Machida H, Kubota I. Nemoto T, et al. EXCLI J. 2017 Jun 20;16:914-920. doi: 10.17179/excli2017-325. eCollection 2017. EXCLI J. 2017. PMID: 28900373 Free PMC article.
However, involvement of MafB for the development of TAMs is unknown. This study was designed to investigate the role of MafB in a murine urethane-induced lung cancer model. ...MafB silencing using dominant-negative MafB did not influence the ini …
However, involvement of MafB for the development of TAMs is unknown. This study was designed to investigate the role of MafB i …
The molecular classification of multiple myeloma.
Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, Gupta S, Epstein J, Yaccoby S, Sawyer J, Burington B, Anaissie E, Hollmig K, Pineda-Roman M, Tricot G, van Rhee F, Walker R, Zangari M, Crowley J, Barlogie B, Shaughnessy JD Jr. Zhan F, et al. Blood. 2006 Sep 15;108(6):2020-8. doi: 10.1182/blood-2005-11-013458. Epub 2006 May 25. Blood. 2006. PMID: 16728703 Free PMC article.
Seven disease subtypes were validated that were strongly influenced by known genetic lesions, such as c-MAF- and MAFB-, CCND1- and CCND3-, and MMSET-activating translocations and hyperdiploidy. Indicative of the deregulation of common pathways by gene orthologs, common gen …
Seven disease subtypes were validated that were strongly influenced by known genetic lesions, such as c-MAF- and MAFB-, CCND1- and CC …
Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.
Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E. Goudot C, et al. Immunity. 2017 Sep 19;47(3):582-596.e6. doi: 10.1016/j.immuni.2017.08.016. Immunity. 2017. PMID: 28930664 Free article.
Using an in vitro culture model yielding human mo-DCs and mo-Macs closely resembling those found in vivo in ascites, we show that IRF4 and MAFB were critical regulators of monocyte differentiation into mo-DCs and mo-Macs, respectively. ...
Using an in vitro culture model yielding human mo-DCs and mo-Macs closely resembling those found in vivo in ascites, we show that IRF4 and …
Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.
Goswami S, Raychaudhuri D, Singh P, Natarajan SM, Chen Y, Poon C, Hennessey M, Tannir AJ, Zhang J, Anandhan S, Kerrigan BP, Macaluso MD, He Z, Jindal S, Lang FF, Basu S, Sharma P. Goswami S, et al. Nat Cancer. 2023 Oct;4(10):1455-1473. doi: 10.1038/s43018-023-00620-0. Epub 2023 Aug 31. Nat Cancer. 2023. PMID: 37653141
Mechanistic studies showed that the absence of Kdm6b enhances antigen presentation, interferon response and phagocytosis in myeloid cells by inhibition of mediators of immune suppression including Mafb, Socs3 and Sirpa. Further, pharmacological inhibition of KDM6B mirrored …
Mechanistic studies showed that the absence of Kdm6b enhances antigen presentation, interferon response and phagocytosis in myeloid cells by …
MAFB promotes the malignant phenotypes by IGFBP6 in esophageal squamous cell carcinomas.
Zhang S, Gong T, Nan Y, Feng R, Liu Z, Chen H. Zhang S, et al. Exp Cell Res. 2022 Jul 1;416(1):113158. doi: 10.1016/j.yexcr.2022.113158. Epub 2022 Apr 14. Exp Cell Res. 2022. PMID: 35430273 Review.
Functional assays show that knockdown of MAFB significantly suppresses cell growth, migration and invasion. Mechanistic investigation demonstrates that MAFB exerts its function by upregulating IGFBP6. Our findings suggest that MAFB may play a tumor-promoting …
Functional assays show that knockdown of MAFB significantly suppresses cell growth, migration and invasion. Mechanistic investigation …
RECQL4, Negatively Regulated by miR-10a-5p, Facilitates Cell Proliferation and Invasion via MAFB in Ovarian Cancer.
Guo L, Li Y, Zhao C, Peng J, Song K, Chen L, Zhang P, Ma H, Yuan C, Yan S, Fang Y, Kong B. Guo L, et al. Front Oncol. 2020 Sep 4;10:524128. doi: 10.3389/fonc.2020.524128. eCollection 2020. Front Oncol. 2020. PMID: 33014878 Free PMC article.
The high frequency of somatic copy number alterations, as opposed to point mutations, is considered a unique feature of ovarian cancer. Amplification-dependent overexpression of RecQ protein-like 4 (RECQL4), which participates in DNA replication and repair, mediates the de …
The high frequency of somatic copy number alterations, as opposed to point mutations, is considered a unique feature of ovarian cancer …
Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing.
Inoue Y, Liao CW, Tsunakawa Y, Tsai IL, Takahashi S, Hamada M. Inoue Y, et al. Int J Mol Sci. 2022 Aug 19;23(16):9346. doi: 10.3390/ijms23169346. Int J Mol Sci. 2022. PMID: 36012611 Free PMC article.
Comparison of the skin wound repair rates in macrophage-specific, MAFB-deficient mice (Mafb(f/f)::LysM-Cre) and control mice (Mafb(f/f)) showed that wound healing was significantly delayed in the former. ...Hence, the MAFB-expressing macrophage populat …
Comparison of the skin wound repair rates in macrophage-specific, MAFB-deficient mice (Mafb(f/f)::LysM-Cre) and control mice ( …
148 results