Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2007 1
2011 1
2013 1
2014 2
2015 3
2016 10
2017 3
2018 10
2019 7
2020 10
2021 10
2022 12
2023 18
2024 4

Text availability

Article attribute

Article type

Publication date

Search Results

81 results

Results by year

Filters applied: . Clear all
Page 1
Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis.
Zha Q, Wu X, Zhang J, Xu T, Shi Y, Sun Y, Fang Y, Gu Y, Ma P, Shu Y, Tian S. Zha Q, et al. Cell Death Discov. 2022 Mar 30;8(1):144. doi: 10.1038/s41420-022-00954-1. Cell Death Discov. 2022. PMID: 35354791 Free PMC article.
Here, hsa_circ_0007967 was highly expressed in gastric cancer tissues than adjacent normal tissues. Overexpressing hsa_circ_0007967 promoted gastric cancer cell proliferation in vitro and in vivo, while suppression of hsa_circ_0007967 inhibited gastric cancer …
Here, hsa_circ_0007967 was highly expressed in gastric cancer tissues than adjacent normal tissues. Overexpressing hsa_circ_0007967 p …
MAML3 Contributes to Induction of Malignant Phenotype of Gallbladder Cancer Through Morphogenesis Signalling Under Hypoxia.
Na L, Onishi H, Morisaki S, Ichimiya S, Yamada Y, Masuda S, Nagao S, Koga S, Nakayama K, Imaizumi A, Oda Y, Nakamura M. Na L, et al. Anticancer Res. 2023 Jul;43(7):2909-2922. doi: 10.21873/anticanres.16462. Anticancer Res. 2023. PMID: 37351966 Free article.
BACKGROUND/AIM: Hedgehog (HH) signalling is a potential therapeutic target for gallbladder cancer (GBC), and Mastermind-like 3 (MAML3) is involved in the transcription of Smoothened (SMO), which is a key protein of HH signalling during hypoxia in the cancer m …
BACKGROUND/AIM: Hedgehog (HH) signalling is a potential therapeutic target for gallbladder cancer (GBC), and Mastermind-like 3 (MA …
Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
Fishbein L, Leshchiner I, Walter V, Danilova L, Robertson AG, Johnson AR, Lichtenberg TM, Murray BA, Ghayee HK, Else T, Ling S, Jefferys SR, de Cubas AA, Wenz B, Korpershoek E, Amelio AL, Makowski L, Rathmell WK, Gimenez-Roqueplo AP, Giordano TJ, Asa SL, Tischler AS; Cancer Genome Atlas Research Network; Pacak K, Nathanson KL, Wilkerson MD. Fishbein L, et al. Cancer Cell. 2017 Feb 13;31(2):181-193. doi: 10.1016/j.ccell.2017.01.001. Epub 2017 Feb 2. Cancer Cell. 2017. PMID: 28162975 Free PMC article.
We identified CSDE1 as a somatically mutated driver gene, complementing four known drivers (HRAS, RET, EPAS1, and NF1). We also discovered fusion genes in PCCs/PGLs, involving MAML3, BRAF, NGFR, and NF1. Integrated analysis classified PCCs/PGLs into four molecularly define …
We identified CSDE1 as a somatically mutated driver gene, complementing four known drivers (HRAS, RET, EPAS1, and NF1). We also discovered f …
RBPJ and MAML3: Potential Therapeutic Targets for Small Cell Lung Cancer.
Onishi H, Ichimiya S, Yanai K, Umebayashi M, Nakamura K, Yamasaki A, Imaizumi A, Nagai S, Murahashi M, Ogata H, Morisaki T. Onishi H, et al. Anticancer Res. 2018 Aug;38(8):4543-4547. doi: 10.21873/anticanres.12758. Anticancer Res. 2018. PMID: 30061220
BACKGROUND/AIM: Small cell lung cancer (SCLC) is still a deadly type of cancer for which there are few effective therapeutic strategies. ...Previously we showed that recombination signal binding protein for immunoglobulin-kappa-J region (RBPJ) and mastermind-like 3 …
BACKGROUND/AIM: Small cell lung cancer (SCLC) is still a deadly type of cancer for which there are few effective therapeutic s …
BCOR involvement in cancer.
Astolfi A, Fiore M, Melchionda F, Indio V, Bertuccio SN, Pession A. Astolfi A, et al. Epigenomics. 2019 May;11(7):835-855. doi: 10.2217/epi-2018-0195. Epub 2019 May 31. Epigenomics. 2019. PMID: 31150281 Free PMC article. Review.
This review provides a comprehensive summary of BCOR's involvement in oncology, illustrating that various BCOR aberrations, such as the internal tandem duplications of the PCGF Ub-like fold discriminator domain and different gene fusions (mainly BCOR-CCNB3, BCOR-MAML3 and …
This review provides a comprehensive summary of BCOR's involvement in oncology, illustrating that various BCOR aberrations, such as the inte …
Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.
Calsina B, Piñeiro-Yáñez E, Martínez-Montes ÁM, Caleiras E, Fernández-Sanromán Á, Monteagudo M, Torres-Pérez R, Fustero-Torre C, Pulgarín-Alfaro M, Gil E, Letón R, Jiménez S, García-Martín S, Martin MC, Roldán-Romero JM, Lanillos J, Mellid S, Santos M, Díaz-Talavera A, Rubio Á, González P, Hernando B, Bechmann N, Dona M, Calatayud M, Guadalix S, Álvarez-Escolá C, Regojo RM, Aller J, Del Olmo-Garcia MI, López-Fernández A, Fliedner SMJ, Rapizzi E, Fassnacht M, Beuschlein F, Quinkler M, Toledo RA, Mannelli M, Timmers HJ, Eisenhofer G, Rodríguez-Perales S, Domínguez O, Macintyre G, Currás-Freixes M, Rodríguez-Antona C, Cascón A, Leandro-García LJ, Montero-Conde C, Roncador G, García-García JF, Pacak K, Al-Shahrour F, Robledo M. Calsina B, et al. Nat Commun. 2023 Feb 28;14(1):1122. doi: 10.1038/s41467-023-36769-6. Nat Commun. 2023. PMID: 36854674 Free PMC article.
Specifically, we define a general immunosuppressive microenvironment in mPPGLs, the exception being PD-L1 expressing MAML3-related tumors. Our study reveals canonical markers for risk of metastasis, and suggests the usefulness of including immune parameters in clinical man …
Specifically, we define a general immunosuppressive microenvironment in mPPGLs, the exception being PD-L1 expressing MAML3-related tu …
Mastermind Like Transcriptional Coactivator 3 (MAML3) Drives Neuroendocrine Tumor Progression.
Alzofon N, Koc K, Panwell K, Pozdeyev N, Marshall CB, Albuja-Cruz M, Raeburn CD, Nathanson KL, Cohen DL, Wierman ME, Kiseljak-Vassiliades K, Fishbein L. Alzofon N, et al. Mol Cancer Res. 2021 Sep;19(9):1476-1485. doi: 10.1158/1541-7786.MCR-20-0992. Epub 2021 May 13. Mol Cancer Res. 2021. PMID: 33986121 Free PMC article.
Metastatic disease in pheochromocytomas and paragangliomas (PCC/PGL) is not well-understood. The Cancer Genome Atlas discovered recurrent MAML3 fusion genes in a subset of tumors that lacked known germline or somatic driver mutations and were associated with aggress …
Metastatic disease in pheochromocytomas and paragangliomas (PCC/PGL) is not well-understood. The Cancer Genome Atlas discovered recur …
MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer.
Li J, Li T, Lu Y, Shen G, Guo H, Wu J, Lei C, Du F, Zhou F, Zhao X, Nie Y, Fan D. Li J, et al. FASEB J. 2017 Sep;31(9):3774-3786. doi: 10.1096/fj.201601140RR. Epub 2017 May 16. FASEB J. 2017. PMID: 28512191
We identified the role and underlying mechanisms of miR-2392 in gastric cancer (GC) metastasis. MiR-2392 was down-regulated in GC cell lines and tissues, and overexpression of miR-2392 significantly inhibited GC invasion and metastasis in vitro and in vivo We identified …
We identified the role and underlying mechanisms of miR-2392 in gastric cancer (GC) metastasis. MiR-2392 was down-regulated in GC cel …
BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR. Kao YC, et al. Am J Surg Pathol. 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. Am J Surg Pathol. 2018. PMID: 29300189 Free PMC article.
The morphologic features and immunoprofile showed considerable overlap with other round cell sarcomas with BCOR oncogenic upregulation, that is, BCOR-MAML3 and BCOR ITD. Follow-up available in 22 patients showed a 5-year overall survival of 72%, which was relatively simila …
The morphologic features and immunoprofile showed considerable overlap with other round cell sarcomas with BCOR oncogenic upregulation, that …
Protein-bound Polysaccharide-K Inhibits Hedgehog Signaling Through Down-regulation of MAML3 and RBPJ Transcription Under Hypoxia, Suppressing the Malignant Phenotype in Pancreatic Cancer.
Yamasaki A, Onishi H, Imaizumi A, Kawamoto M, Fujimura A, Oyama Y, Katano M. Yamasaki A, et al. Anticancer Res. 2016 Aug;36(8):3945-52. Anticancer Res. 2016. PMID: 27466498
PSK reduced SMO, MAML3 and RBPJ expression in pancreatic cancer cells under hypoxia. ...These results suggest that PSK suppresses Hedgehog signaling through down-regulation of MAML3 and RBPJ transcription under hypoxia, inhibiting the induction of a malignant …
PSK reduced SMO, MAML3 and RBPJ expression in pancreatic cancer cells under hypoxia. ...These results suggest that PSK suppres …
81 results