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Retraction Note to: MicroRNA-23 regulates the growth, metastasis and chemosensitivity of human gastric cancer cells by targeting MAP3K9.
Li D, Wang J, Hui Y, Yang Y, Peng X, Sun C. Li D, et al. J BUON. 2021 Jul-Aug;26(4):1695. J BUON. 2021. PMID: 34565051 Free article.
Retraction of "MicroRNA-23 regulates the growth, metastasis and chemosensitivity of human gastric cancer cells by targeting MAP3K9", by Deping Li, Juan Wang, Yuanjian Hui, Yan Yang, Xingchun Peng, Shengbao Li, Chuantao Sun. ...
Retraction of "MicroRNA-23 regulates the growth, metastasis and chemosensitivity of human gastric cancer cells by targeting MAP3K9
MicroRNA-23 regulates the growth, metastasis and chemosensitivity of human gastric cancer cells by targeting MAP3K9.
Li D, Wang J, Hui Y, Yang Y, Peng X, Li S, Sun C. Li D, et al. J BUON. 2020 Sep-Oct;25(5):2315-2321. J BUON. 2020. PMID: 33277851 Free article. Retracted.
Furthermore, miR-23 also inhibited the migration and invasion of cancer cells. MAP3K9 was shown to be the target gene of miR-23 and silencing of MAP3K9 was seen to mimic the growth inhibitory effect of miR-23. Overexpression of MAP3K9 reversed the grow …
Furthermore, miR-23 also inhibited the migration and invasion of cancer cells. MAP3K9 was shown to be the target gene of miR-2 …
miR-7 Suppresses Tumor Progression by Directly Targeting MAP3K9 in Pancreatic Cancer.
Xia J, Cao T, Ma C, Shi Y, Sun Y, Wang ZP, Ma J. Xia J, et al. Mol Ther Nucleic Acids. 2018 Dec 7;13:121-132. doi: 10.1016/j.omtn.2018.08.012. Epub 2018 Aug 22. Mol Ther Nucleic Acids. 2018. PMID: 30290304 Free PMC article.
Extensive research has suggested that miR-7 plays a critical role in cancer progression. However, the biological function of miR-7 in pancreatic cancer (PC) progression is poorly understood. ...Taken together, these results suggest that miR-7/MAP3K9 is critic …
Extensive research has suggested that miR-7 plays a critical role in cancer progression. However, the biological function of miR-7 in …
Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.
Fawdar S, Trotter EW, Li Y, Stephenson NL, Hanke F, Marusiak AA, Edwards ZC, Ientile S, Waszkowycz B, Miller CJ, Brognard J. Fawdar S, et al. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12426-31. doi: 10.1073/pnas.1305207110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836671 Free PMC article.
This remains a major challenge as the underlying genetic causes of ~50% of non-small-cell lung cancers remain unknown. Here we demonstrate that a targeted genetic dependency screen is an efficient approach to identify somatic cancer alterations that are functionally …
This remains a major challenge as the underlying genetic causes of ~50% of non-small-cell lung cancers remain unknown. Here we demons …
Circ_SIPA1L1 Promotes Osteosarcoma Progression Via miR-379-5p/MAP3K9 Axis.
Jun L, Xuhong L, Hui L. Jun L, et al. Cancer Biother Radiopharm. 2023 Nov;38(9):604-618. doi: 10.1089/cbr.2020.3891. Epub 2020 Sep 4. Cancer Biother Radiopharm. 2023. PMID: 32897735
Western blot assay was used to measure the expression of metastasis-related proteins and MAP3K9. The target interactions between the genes in circ_SIPA1L1/miR-379-5p/MAP3K9 axis were predicted by StarBase and confirmed by dual-luciferase reporter assay. ...Circ_SIPA …
Western blot assay was used to measure the expression of metastasis-related proteins and MAP3K9. The target interactions between the …
Promoter methylation-regulated miR-148a-3p inhibits lung adenocarcinoma (LUAD) progression by targeting MAP3K9.
Liang L, Xu WY, Shen A, Cen HY, Chen ZJ, Tan L, Zhang LM, Zhang Y, Fu JJ, Qin AP, Lei XP, Li SP, Qin YY, Huang JH, Yu XY. Liang L, et al. Acta Pharmacol Sin. 2022 Nov;43(11):2946-2955. doi: 10.1038/s41401-022-00893-8. Epub 2022 Apr 6. Acta Pharmacol Sin. 2022. PMID: 35388129 Free PMC article.
We demonstrated that mitogen-activated protein (MAP) kinase kinase kinase 9 (MAP3K9) was the target of miR-148a-3p and that MAP3K9 levels were significantly increased in both LUAD cell lines and clinical tumor tissues. ...Taken together, the promoter methylation-ass …
We demonstrated that mitogen-activated protein (MAP) kinase kinase kinase 9 (MAP3K9) was the target of miR-148a-3p and that MAP3K9
MicroRNA-148b enhances proliferation and apoptosis in human renal cancer cells via directly targeting MAP3K9.
Nie F, Liu T, Zhong L, Yang X, Liu Y, Xia H, Liu X, Wang X, Liu Z, Zhou L, Mao Z, Zhou Q, Chen T. Nie F, et al. Mol Med Rep. 2016 Jan;13(1):83-90. doi: 10.3892/mmr.2015.4555. Epub 2015 Nov 11. Mol Med Rep. 2016. PMID: 26573018 Free PMC article.
The present study aimed to verify the potential roles of miR148b in human renal cancer cells. miR-148b was found to be downregulated in human renal cancel tissues and human renal cancer cell lines. ...In addition, overexpression of MAP3K9 and pJNK was detecte …
The present study aimed to verify the potential roles of miR148b in human renal cancer cells. miR-148b was found to be downregulated …
Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.
Quinn LM, Haldenby S, Antzcak P, Fowler A, Bullock K, Kenny J, Gilbert T, Andrews T, Diaz-Nieto R, Fenwick S, Jones R, Costello-Goldring E, Poston G, Greenhalf W, Palmer D, Malik H, Goldring C. Quinn LM, et al. Sci Rep. 2023 Apr 24;13(1):6681. doi: 10.1038/s41598-023-33096-0. Sci Rep. 2023. PMID: 37095160 Free PMC article.

We identified non-synonymous mutation (p.Glu38del) in MAP3K9 in ten tumors, associated with increased peri-vascular invasion (Fisher's exact, p < 0.018). ...We also identified a targetable MAP3K9 mutation, in addition to oncogenic and immunological pathways hithe

We identified non-synonymous mutation (p.Glu38del) in MAP3K9 in ten tumors, associated with increased peri-vascular invasion (Fisher' …
Circular RNA circSEC24A Promotes Cutaneous Squamous Cell Carcinoma Progression by Regulating miR-1193/MAP3K9 Axis.
Lu X, Gan Q, Gan C. Lu X, et al. Onco Targets Ther. 2021 Jan 22;14:653-666. doi: 10.2147/OTT.S275691. eCollection 2021. Onco Targets Ther. 2021. PMID: 33519212 Free PMC article.
Moreover, miR-1193 was a direct target of circSEC24A and its downregulation reversed the inhibitory effect of circSEC24A knockdown on the progression of CSCC cells. Furthermore, MAP3K9 was a downstream target of miR-1193 and its upregulation attenuated the anti-cancer
Moreover, miR-1193 was a direct target of circSEC24A and its downregulation reversed the inhibitory effect of circSEC24A knockdown on the pr …
Elevation of miR-125b-5p is related to improved prognosis in laryngeal squamous cell carcinoma and inhibits the malignancy and glycometabolic disorder by targeting MAP3K9.
Chen F, Lao Z, Zhang HY, Wang J, Wang SZ. Chen F, et al. Neoplasma. 2022 May;69(3):550-559. doi: 10.4149/neo_2022_211027N1532. Epub 2022 Feb 22. Neoplasma. 2022. PMID: 35188403
Laryngeal squamous cell carcinoma (LSCC) is the most common malignant tumor in the head and neck cancer, with a poor prognosis. As we know, microRNAs (miRNAs) play a vital role in the initiation and development of various cancers including LSCC. ...And miR-125b-5p s …
Laryngeal squamous cell carcinoma (LSCC) is the most common malignant tumor in the head and neck cancer, with a poor prognosis. As we …
39 results