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2008 1
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2012 3
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2014 1
2015 4
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2020 4
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51 results

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IncRNA MAPKAPK5-AS1 promotes proliferation and migration of thyroid cancer cell lines by targeting miR-519e-5p/YWHAH.
Zhou Y, Liu S, Luo Y, Zhang M, Jiang X, Xiong Y. Zhou Y, et al. Eur J Histochem. 2020 Dec 3;64(4):3177. doi: 10.4081/ejh.2020.3177. Eur J Histochem. 2020. PMID: 33272009 Free PMC article.
An extensive body of evidence has demonstrated that lncRNAs play a critical role in the progression of thyroid cancer. The lncRNA MAPKAPK5-AS1 has been reported to be abnormally expressed and to play a role in the development of various human cancers. However …
An extensive body of evidence has demonstrated that lncRNAs play a critical role in the progression of thyroid cancer. The lncRNA …
MAPKAPK5-AS1/miR-515-5p/CAB39 Axis Contributes to Non-small Cell Lung Cancer Cell Proliferation and Migration.
Zhao Y, Zhou D, Yuan Y, Chen Y, Zhang K, Tan Y, Fang S. Zhao Y, et al. Mol Biotechnol. 2023 Nov;65(11):1887-1897. doi: 10.1007/s12033-023-00654-w. Epub 2023 Mar 3. Mol Biotechnol. 2023. PMID: 36867352
Several studies have elucidated the pivotal function that long noncoding RNAs (lncRNAs) exerted on the initiation and development of various human carcinomas, encompassing non-small cell lung cancer (NSCLC). In spite of the fact that lncRNA MAPKAPK5 antisense RNA 1 …
Several studies have elucidated the pivotal function that long noncoding RNAs (lncRNAs) exerted on the initiation and development of various …
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer proliferation by partly silencing p21 expression.
Ji H, Hui B, Wang J, Zhu Y, Tang L, Peng P, Wang T, Wang L, Xu S, Li J, Wang K. Ji H, et al. Cancer Sci. 2019 Jan;110(1):72-85. doi: 10.1111/cas.13838. Epub 2018 Dec 4. Cancer Sci. 2019. PMID: 30343528 Free PMC article.
We also found that p21 is a target of MAPKAPK5-AS1. In addition, we are the first to report that MAPKAPK5-AS1 plays a carcinogenic role in CRC. MAPKAPK5-AS1 is a novel prognostic biomarker and a potential therapeutic candidate for CRC cancer....
We also found that p21 is a target of MAPKAPK5-AS1. In addition, we are the first to report that MAPKAPK5-AS1 plays a carcinog …
Long non-coding RNA MAPKAPK5-AS1/PLAGL2/HIF-1alpha signaling loop promotes hepatocellular carcinoma progression.
Wang L, Sun L, Liu R, Mo H, Niu Y, Chen T, Wang Y, Han S, Tu K, Liu Q. Wang L, et al. J Exp Clin Cancer Res. 2021 Feb 17;40(1):72. doi: 10.1186/s13046-021-01868-z. J Exp Clin Cancer Res. 2021. PMID: 33596983 Free PMC article.
MAPKAPK5-AS1 has been recognized as an oncogene in colorectal cancer. ...Furthermore, MAPKAPK5-AS1 silencing suppressed, while MAPKAPK5-AS1 overexpression enhanced HCC growth and lung metastasis in vivo. ...
MAPKAPK5-AS1 has been recognized as an oncogene in colorectal cancer. ...Furthermore, MAPKAPK5-AS1 silencing suppressed …
High level of LncRNA MAPKAPK5-AS1 predicts poor prognosis and contributes to the malignant proliferation and EMT of non-small cell lung cancer via sponging miR-490-3p from HMGB2.
Miao J, Gao Y, Guan W, Yu X, Wang Y, Jiang P, Yang L, Xu L, You W. Miao J, et al. Genes Genomics. 2023 May;45(5):611-625. doi: 10.1007/s13258-022-01339-5. Epub 2022 Nov 29. Genes Genomics. 2023. PMID: 36445573
OBJECTIVE: To investigate whether MAPKAPK5-AS1 affected the malignant progression of NSCLC. METHODS: The levels of MAPKAPK5-AS1, miR-490-3p and HMGB2 in lung cancer were first analyzed through StarBase website, and confirmed by a quantitative reverse transcri …
OBJECTIVE: To investigate whether MAPKAPK5-AS1 affected the malignant progression of NSCLC. METHODS: The levels of MAPKAPK5-AS …
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge.
Yang T, Chen WC, Shi PC, Liu MR, Jiang T, Song H, Wang JQ, Fan RZ, Pei DS, Song J. Yang T, et al. J Exp Clin Cancer Res. 2020 Jul 20;39(1):139. doi: 10.1186/s13046-020-01633-8. J Exp Clin Cancer Res. 2020. PMID: 32690100 Free PMC article.
BACKGROUND: Long noncoding RNAs (lncRNAs) are considered critical regulators in cancers; however, the clinical significance and mechanisms of MAPKAPK5-AS1 (hereinafter referred to as MK5-AS1) in colorectal cancer (CRC) remain mostly unknown. ...
BACKGROUND: Long noncoding RNAs (lncRNAs) are considered critical regulators in cancers; however, the clinical significance and mecha …
MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis.
Peng Z, Ouyang X, Wang Y, Fan Q. Peng Z, et al. BMC Mol Cell Biol. 2022 Apr 25;23(1):21. doi: 10.1186/s12860-022-00420-x. BMC Mol Cell Biol. 2022. PMID: 35468721 Free PMC article.
MiR-429 was validated to be the target of MAPKAPK5-AS1, and miR-429 inhibitors could partially offset the effects of knocking down MAPKAPK5-AS1 on HCC cells. MAPKAPK5-AS1 could positively regulate ZEB1 expression through repressing miR-429. ...
MiR-429 was validated to be the target of MAPKAPK5-AS1, and miR-429 inhibitors could partially offset the effects of knocking down …
The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis.
Zhao Z, Wang Y, Gao Y, Ju Y, Zhao Y, Wu Z, Gao S, Zhang B, Pang X, Zhang Y, Wang W. Zhao Z, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2212613120. doi: 10.1073/pnas.2212613120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126714 Free PMC article.
Oxidative stress is a key feature in both chronic inflammation and cancer. P38 regulated/activated protein kinase (PRAK) deficiency can cause functional disorders in neutrophils and macrophages under high oxidative stress, but the precise mechanisms by which PRAK regulates …
Oxidative stress is a key feature in both chronic inflammation and cancer. P38 regulated/activated protein kinase (PRAK) deficiency c …
Upregulation of MAPKAPK5-AS1, PXN-AS1 and URB1-AS1 lncRNAs in non-functioning pituitary adenoma.
Taheri M, Safarzadeh A, Bahranian A, Eslami S, Dilmaghani NA, Ghafouri-Fard S, Sharifi G. Taheri M, et al. J Cell Mol Med. 2023 Jun;27(11):1550-1556. doi: 10.1111/jcmm.17763. Epub 2023 May 8. J Cell Mol Med. 2023. PMID: 37154079 Free PMC article.
Besides, relative expression levels of MAPKAPK5-AS1 and LIFR-AS1 were associated with gender of patients (p values = 0.043 and 0.01, respectively). Cumulatively, the current study indicates the possible role of MAPKAPK5-AS1, PXN-AS1 and URB1-AS1 lncRNAs in the patho …
Besides, relative expression levels of MAPKAPK5-AS1 and LIFR-AS1 were associated with gender of patients (p values = 0.043 and 0.01, …
51 results