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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 4
1997 2
1998 4
1999 3
2000 1
2001 3
2002 5
2003 8
2004 6
2005 8
2006 14
2007 15
2008 18
2009 18
2010 24
2011 23
2012 17
2013 14
2014 23
2015 32
2016 18
2017 30
2018 21
2019 28
2020 30
2021 35
2022 29
2023 10
2024 10

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404 results

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Page 1
PRMT5 promotes colorectal cancer growth by interaction with MCM7.
Li X, Wang X, Zhao J, Wang J, Wu J. Li X, et al. J Cell Mol Med. 2021 Apr;25(7):3537-3547. doi: 10.1111/jcmm.16436. Epub 2021 Mar 6. J Cell Mol Med. 2021. PMID: 33675123 Free PMC article.
In addition, our results from analysis of 99 CRC tissues and 77 adjacent non-cancerous tissues indicated that the PRMT5 and MCM7 expression levels were significantly higher in CRC tissues than in control tissues, which was further confirmed by bioinformatic analysis …
In addition, our results from analysis of 99 CRC tissues and 77 adjacent non-cancerous tissues indicated that the PRMT5 and MCM7 …
MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux.
Mo L, Su B, Xu L, Hu Z, Li H, Du H, Li J. Mo L, et al. iScience. 2022 Aug 28;25(9):105029. doi: 10.1016/j.isci.2022.105029. eCollection 2022 Sep 16. iScience. 2022. PMID: 36111256 Free PMC article.
In these slow-cycling BCSLCs, the DNA replication initiator MCM7 is required for autophagy and stemness. MCM7 knockdown inhibits autophagic flux and reduces the stemness of BCSLCs. MCM7 can facilitate autolysosome formation through binding with dynein to prom …
In these slow-cycling BCSLCs, the DNA replication initiator MCM7 is required for autophagy and stemness. MCM7 knockdown inhibi …
In silico investigation of the role of vitamins in cancer therapy through inhibition of MCM7 oncoprotein.
Mukherjee S, Das S, Sriram N, Chakraborty S, Sah MK. Mukherjee S, et al. RSC Adv. 2022 Oct 31;12(48):31004-31015. doi: 10.1039/d2ra03703c. eCollection 2022 Oct 27. RSC Adv. 2022. PMID: 36349041 Free PMC article.
Inhibition of MCM7 may lead to a significant reduction in cancer-associated cell proliferation. ...This significantly halts the structure-guided ligand designing for cancer therapy targeting the MCM7. The present study aims to resolve the tertiary stru …
Inhibition of MCM7 may lead to a significant reduction in cancer-associated cell proliferation. ...This significantly halts th …
MCM7 affects the cisplatin resistance of liver cancer cells and the development of liver cancer by regulating the PI3K/Akt signaling pathway.
Su D. Su D. Immunopharmacol Immunotoxicol. 2022 Feb;44(1):17-27. doi: 10.1080/08923973.2021.1991372. Epub 2021 Nov 25. Immunopharmacol Immunotoxicol. 2022. PMID: 34821526
The effect of MCM7 on cell proliferation, apoptosis, and drug resistance of liver cancer and its mechanism were investigated in this study. METHODS: MCM7 expression in normal liver cells, liver cancer cell lines, and tissues, as well as adjacent tissue …
The effect of MCM7 on cell proliferation, apoptosis, and drug resistance of liver cancer and its mechanism were investigated i …
miR-107 regulates the effect of MCM7 on the proliferation and apoptosis of colorectal cancer via the PAK2 pathway.
Zhao M, Wang Y, Jiang C, Wang Q, Mi J, Zhang Y, Zuo L, Geng Z, Song X, Ge S, Li J, Wen H, Wang J, Wang Z, Su F. Zhao M, et al. Biochem Pharmacol. 2021 Aug;190:114610. doi: 10.1016/j.bcp.2021.114610. Epub 2021 May 16. Biochem Pharmacol. 2021. PMID: 34010598 Free article.
MCM7 is reported to be involved in tumor formation and progression, whereas the expression profile and molecular function of MCM7 in colorectal cancer (CRC) remain unknown. ...Taken together, our results suggest that the miR-107/MCM7/PAK2 pathway may p …
MCM7 is reported to be involved in tumor formation and progression, whereas the expression profile and molecular function of MCM7 …
Good or not good: Role of miR-18a in cancer biology.
Kolenda T, Guglas K, Kopczyńska M, Sobocińska J, Teresiak A, Bliźniak R, Lamperska K. Kolenda T, et al. Rep Pract Oncol Radiother. 2020 Sep-Oct;25(5):808-819. doi: 10.1016/j.rpor.2020.07.006. Epub 2020 Aug 12. Rep Pract Oncol Radiother. 2020. PMID: 32884453 Free PMC article. Review.
In contrast to the other members, the expression of miR-18a is additionally controlled and probably functions as its own internal controller of the cluster. miR-18a regulates many genes involved in proliferation, cell cycle, apoptosis, response to different kinds of stress, autop …
In contrast to the other members, the expression of miR-18a is additionally controlled and probably functions as its own internal controller …
Computational Screening of Natural Compounds for Identification of Potential Anti-Cancer Agents Targeting MCM7 Protein.
Alshahrani MY, Alshahrani KM, Tasleem M, Akeel A, Almeleebia TM, Ahmad I, Asiri M, Alshahrani NA, Alabdallah NM, Saeed M. Alshahrani MY, et al. Molecules. 2021 Sep 28;26(19):5878. doi: 10.3390/molecules26195878. Molecules. 2021. PMID: 34641424 Free PMC article.
Minichromosome maintenance complex component 7 (MCM7) is involved in replicative licensing and the synthesis of DNA, and its overexpression is a fascinating biomarker for various cancer types. There is currently no effective agent that can prevent the development of …
Minichromosome maintenance complex component 7 (MCM7) is involved in replicative licensing and the synthesis of DNA, and its overexpr …
Phospholipase PLCE1 Promotes Transcription and Phosphorylation of MCM7 to Drive Tumor Progression in Esophageal Cancer.
Shi Q, Xu G, Jiang Y, Yang J, Han X, Wang Q, Li Y, Zhang Z, Wang K, Peng H, Chen F, Ma Y, Zhao L, Chen Y, Liu Z, Yang L, Jia X, Wen T, Tong Z, Cui X, Li F. Shi Q, et al. Cancer Res. 2024 Feb 15;84(4):560-576. doi: 10.1158/0008-5472.CAN-23-1633. Cancer Res. 2024. PMID: 38117512
Inhibition of PLCE1 or RIOK2 hampered MCM7-mediated DNA replication, resulting in G1-S arrest. Furthermore, MCM7 overexpression in ESCC correlated with poor patient survival. ...SIGNIFICANCE: PLCE1 promotes tumor progression in ESCC by activating PKCalpha-mediated p …
Inhibition of PLCE1 or RIOK2 hampered MCM7-mediated DNA replication, resulting in G1-S arrest. Furthermore, MCM7 overexpressio …
MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma.
Qu K, Wang Z, Fan H, Li J, Liu J, Li P, Liang Z, An H, Jiang Y, Lin Q, Dong X, Liu P, Liu C. Qu K, et al. Cell Death Dis. 2017 Feb 9;8(2):e2603. doi: 10.1038/cddis.2016.352. Cell Death Dis. 2017. PMID: 28182015 Free PMC article.
Cyclin D1 was proved to be regulated by MCM7-MAPK signaling pathway. Clinically, high expression of both MCM7 and cyclin D1 exhibited a relatively high sensitivity and specificity to predict worse outcome of HCC patients. Taken together, our results suggest that …
Cyclin D1 was proved to be regulated by MCM7-MAPK signaling pathway. Clinically, high expression of both MCM7 and cyclin D1 ex …
RACK1 promotes lung cancer cell growth via an MCM7/RACK1/ Akt signaling complex.
Fei L, Ma Y, Zhang M, Liu X, Luo Y, Wang C, Zhang H, Zhang W, Han Y. Fei L, et al. Oncotarget. 2017 Jun 20;8(25):40501-40513. doi: 10.18632/oncotarget.17120. Oncotarget. 2017. PMID: 28465488 Free PMC article.
In this report, we demonstrate that RACK1 regulates cell growth and cell cycle progression in human non-small-cell lung cancer by mediating MCM7 phosphorylation through an MCM7/RACK1/Akt signaling complex. RACK1 functions as a central scaffold that brings Akt …
In this report, we demonstrate that RACK1 regulates cell growth and cell cycle progression in human non-small-cell lung cancer by med …
404 results