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Page 1
Enzyme assay of N-acetylglucosaminyltransferase IX/Vb (MGAT5B).
Inamori KI, Maeda K, Taniguchi N. Inamori KI, et al. 2021 Oct 1 [updated 2022 Mar 15]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. 2021 Oct 1 [updated 2022 Mar 15]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. PMID: 37590707 Free Books & Documents. Review. No abstract available.
Epigenetic Regulation of Glycosylation.
Indellicato R, Trinchera M. Indellicato R, et al. Adv Exp Med Biol. 2021;1325:173-186. doi: 10.1007/978-3-030-70115-4_8. Adv Exp Med Biol. 2021. PMID: 34495535
Essential studies were performed in the brain, where expression of glycogenes like MGAT5B, B4GALNT1, and ST8Sia1 are under the control of histone modifications, and in the immune system, where expression of FUT7 is regulated by both DNA methylation and histone modification …
Essential studies were performed in the brain, where expression of glycogenes like MGAT5B, B4GALNT1, and ST8Sia1 are under the contro …
Human prostate cancer in a clinically relevant xenograft mouse model: identification of beta(1,6)-branched oligosaccharides as a marker of tumor progression.
Lange T, Ullrich S, Müller I, Nentwich MF, Stübke K, Feldhaus S, Knies C, Hellwinkel OJ, Vessella RL, Abramjuk C, Anders M, Schröder-Schwarz J, Schlomm T, Huland H, Sauter G, Schumacher U. Lange T, et al. Clin Cancer Res. 2012 Mar 1;18(5):1364-73. doi: 10.1158/1078-0432.CCR-11-2900. Epub 2012 Jan 18. Clin Cancer Res. 2012. PMID: 22261809
CONCLUSION: We show a novel xenograft mouse model for human prostate cancer respecting the complete metastatic cascade. Specific glycosylation patterns reveal Mgat5b products as relevant markers of both metastatic competence in mice and disease-free survival in pati …
CONCLUSION: We show a novel xenograft mouse model for human prostate cancer respecting the complete metastatic cascade. Specific glyc …
POFUT1 mRNA expression as an independent prognostic parameter in muscle-invasive bladder cancer.
Wahby S, Jarczyk J, Fierek A, Heinkele J, Weis CA, Eckstein M, Martini T, Porubsky S, Hafner M, Erben P. Wahby S, et al. Transl Oncol. 2021 Jan;14(1):100900. doi: 10.1016/j.tranon.2020.100900. Epub 2020 Oct 21. Transl Oncol. 2021. PMID: 33099185 Free PMC article.
Muscle-invasive bladder cancer (MIBC) is characterized by high recurrence and rapid progression. ...Thus, the patients with low POFUT1 mRNA were at a 4.9-fold greater risk for cancer-specific death according to the multivariable analysis (p = 0.0001). ...
Muscle-invasive bladder cancer (MIBC) is characterized by high recurrence and rapid progression. ...Thus, the patients with low POFUT …
Predicting biochemical-recurrence-free survival using a three-metabolic-gene risk score model in prostate cancer patients.
Zhao Y, Tao Z, Li L, Zheng J, Chen X. Zhao Y, et al. BMC Cancer. 2022 Mar 4;22(1):239. doi: 10.1186/s12885-022-09331-8. BMC Cancer. 2022. PMID: 35246070 Free PMC article.
BACKGROUND: Biochemical recurrence (BCR) after initial treatment, such as radical prostatectomy, is the most frequently adopted prognostic factor for patients who suffer from prostate cancer (PCa). In this study, we aimed to construct a prognostic model consisting of gene …
BACKGROUND: Biochemical recurrence (BCR) after initial treatment, such as radical prostatectomy, is the most frequently adopted prognostic f …
Glyco-genes change expression in cancer through aberrant methylation.
Vojta A, Samaržija I, Bočkor L, Zoldoš V. Vojta A, et al. Biochim Biophys Acta. 2016 Aug;1860(8):1776-85. doi: 10.1016/j.bbagen.2016.01.002. Epub 2016 Jan 12. Biochim Biophys Acta. 2016. PMID: 26794090
METHODS: We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using data from publicly available databases. We also analyzed methylation datasets without the available matching expression data for glyco-genes …
METHODS: We analyzed DNA methylation and expression of 86 glyco-genes in melanoma, hepatocellular, breast and cervical cancers using …
Pathological discrimination between luteinized thecoma associated with sclerosing peritonitis and thecoma.
Liu J, Wei J, Yang Y, Wei J. Liu J, et al. Medicine (Baltimore). 2023 Jun 9;102(23):e33911. doi: 10.1097/MD.0000000000033911. Medicine (Baltimore). 2023. PMID: 37335673 Free PMC article.
In addition, the MGAT5B-NCOA3 fusion gene was identified in LTSP for the first time with significantly rich expression compared to thecoma. CONCLUSIONS: We verified 6 significant molecular pathological markers containing MGAT5B, NCOA3, MKI67, beta-Catenin, CD99, and …
In addition, the MGAT5B-NCOA3 fusion gene was identified in LTSP for the first time with significantly rich expression compared to th …
Effects of Epigallocatechin Gallate (EGCG) on Urinary Bladder Urothelial Carcinoma-Next-Generation Sequencing and Bioinformatics Approaches.
Lee HY, Chen YJ, Chang WA, Li WM, Ke HL, Wu WJ, Kuo PL. Lee HY, et al. Medicina (Kaunas). 2019 Dec 1;55(12):768. doi: 10.3390/medicina55120768. Medicina (Kaunas). 2019. PMID: 31805718 Free PMC article.
Background and objectives: Bladder urothelial carcinoma is the most common type of genitourinary cancer. Patients with bladder cancer may have limited treatment efficacy related to drug toxicity, resistance or adverse effects, and novel therapeutic strategies to enh …
Background and objectives: Bladder urothelial carcinoma is the most common type of genitourinary cancer. Patients with bladder can …
The transcriptional profiling of glycogenes associated with hepatocellular carcinoma metastasis.
Liu T, Zhang S, Chen J, Jiang K, Zhang Q, Guo K, Liu Y. Liu T, et al. PLoS One. 2014 Sep 18;9(9):e107941. doi: 10.1371/journal.pone.0107941. eCollection 2014. PLoS One. 2014. PMID: 25232831 Free PMC article.
Four differentially transcribed glycogenes were validated in clinical cancer specimens by qRT-PCR. RESULTS: A total of thirty-three differentially transcribed glycogenes were obtained by comparison the transcription in the metastatic human HCC cell lines (MHCC97L, MHCC97H …
Four differentially transcribed glycogenes were validated in clinical cancer specimens by qRT-PCR. RESULTS: A total of thirty-three d …
Microenvironmental Hypoxia Induces Dynamic Changes in Lung Cancer Synthesis and Secretion of Extracellular Vesicles.
Tse SW, Tan CF, Park JE, Gnanasekaran J, Gupta N, Low JK, Yeoh KW, Chng WJ, Tay CY, McCarthy NE, Lim SK, Sze SK. Tse SW, et al. Cancers (Basel). 2020 Oct 11;12(10):2917. doi: 10.3390/cancers12102917. Cancers (Basel). 2020. PMID: 33050615 Free PMC article.
In addition, functional clustering analyses revealed that tumour hypoxia was strongly associated with rapid synthesis and EV loading of lysosome-related hydrolases and membrane-trafficking proteins to enhance EVs secretion. Moreover, lung cancer-derived EVs were also enric …
In addition, functional clustering analyses revealed that tumour hypoxia was strongly associated with rapid synthesis and EV loading of lyso …
18 results