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A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux.
Allen EA, Amato C, Fortier TM, Velentzas P, Wood W, Baehrecke EH. Allen EA, et al. J Cell Biol. 2020 Nov 2;219(11):e201909073. doi: 10.1083/jcb.201909073. J Cell Biol. 2020. PMID: 32915229 Free PMC article.
CG3530 is homologous to the human MTMR6 subfamily of myotubularin-related 3-phosphatases, and therefore, we named it dMtmr6. dMtmr6, which is required for development and viability in Drosophila, functions as a regulator of autophagic flux in multiple Drosophila cell types. The M …
CG3530 is homologous to the human MTMR6 subfamily of myotubularin-related 3-phosphatases, and therefore, we named it dMtmr6. dMtmr6, which i …
Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme.
Waugh MG. Waugh MG. Mol Neurobiol. 2016 Jan;53(1):621-630. doi: 10.1007/s12035-014-9034-9. Epub 2014 Dec 15. Mol Neurobiol. 2016. PMID: 25502460 Free PMC article.
Structural rearrangements of chromosome 10 are frequently observed in glioblastoma multiforme and over 80 % of tumour samples archived in the catalogue of somatic mutations in cancer database had gene copy number loss for PI4K2A which encodes phosphatidylinositol 4-kinase …
Structural rearrangements of chromosome 10 are frequently observed in glioblastoma multiforme and over 80 % of tumour samples archived in th …
Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.
Appel S, Filter M, Reis A, Hennies HC, Bergheim A, Ogilvie E, Arndt S, Simmons A, Lovett M, Hide W, Ramsay M, Reichwald K, Zimmermann W, Rosenthal A. Appel S, et al. Eur J Hum Genet. 2002 Jan;10(1):17-25. doi: 10.1038/sj.ejhg.5200750. Eur J Hum Genet. 2002. PMID: 11896452
This chromosomal region has also been associated with frequent loss of heterozygosity in different types of cancer. To identify positional candidate genes for keratolytic winter erythema, a BAC contig located between the markers at D8S550 and D8S1695 was constructed and se …
This chromosomal region has also been associated with frequent loss of heterozygosity in different types of cancer. To identify posit …