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Year Number of Results
1995 1
1996 3
1997 5
1998 6
1999 9
2000 10
2001 18
2002 16
2003 21
2004 26
2005 28
2006 34
2007 31
2008 25
2009 22
2010 46
2011 39
2012 43
2013 54
2014 55
2015 43
2016 31
2017 33
2018 46
2019 40
2020 52
2021 56
2022 34
2023 49
2024 20

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795 results

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Page 1
Molecular Alterations in Gastric Preneoplastic Lesions and Early Gastric Cancer.
Battista S, Ambrosio MR, Limarzi F, Gallo G, Saragoni L. Battista S, et al. Int J Mol Sci. 2021 Jun 22;22(13):6652. doi: 10.3390/ijms22136652. Int J Mol Sci. 2021. PMID: 34206291 Free PMC article. Review.
This article reviews the diagnostic and prognostic values of molecular markers in complete (MUC2) and incomplete (MUC2, MUC5AC, and MUC6) intestinal metaplasia, gastric dysplasia/intra-epithelial neoplasia, and early gastric cancer. In particular, considering preinv …
This article reviews the diagnostic and prognostic values of molecular markers in complete (MUC2) and incomplete (MUC2, MUC5AC, and MUC6 …
Regulation of MUC6 Methylation Correlates with Progression of Gastric Cancer.
Shi D, Xi XX. Shi D, et al. Yonsei Med J. 2021 Nov;62(11):1005-1015. doi: 10.3349/ymj.2021.62.11.1005. Yonsei Med J. 2021. PMID: 34672134 Free PMC article.
PURPOSE: This study aimed to investigate the mechanistic downregulation of mucin 6 (MUC6) and its influence on the progression of gastric cancer (GC). ...The methylation levels of MUC6 in GC tissues and GC cell lines were significantly higher than those in pa …
PURPOSE: This study aimed to investigate the mechanistic downregulation of mucin 6 (MUC6) and its influence on the progression of gas …
Glycosylation of MUC6 by alpha1,4-linked N-acetylglucosamine enhances suppression of pancreatic cancer malignancy.
Yuki A, Fujii C, Yamanoi K, Matoba H, Harumiya S, Kawakubo M, Nakayama J. Yuki A, et al. Cancer Sci. 2022 Feb;113(2):576-586. doi: 10.1111/cas.15209. Epub 2021 Nov 28. Cancer Sci. 2022. PMID: 34808019 Free PMC article.
Here, we ectopically expressed alpha4GnT, the alphaGlcNAc biosynthetic enzyme, together with MUC6 in the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, neither of which expresses alpha4GnT and MUC6. ...These results strongly suggest that alphaGlcNA …
Here, we ectopically expressed alpha4GnT, the alphaGlcNAc biosynthetic enzyme, together with MUC6 in the human pancreatic cancer …
Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing.
Zhang M, Hu S, Min M, Ni Y, Lu Z, Sun X, Wu J, Liu B, Ying X, Liu Y. Zhang M, et al. Gut. 2021 Mar;70(3):464-475. doi: 10.1136/gutjnl-2019-320368. Epub 2020 Jun 12. Gut. 2021. PMID: 32532891 Free PMC article.
In addition, we also analysed non-malignant epithelium and provided molecular evidences for potential transition from gastric chief cells into MUC6(+)TFF2(+) spasmolytic polypeptide expressing metaplasia. CONCLUSION: Altogether, our study offers valuable resource for decip …
In addition, we also analysed non-malignant epithelium and provided molecular evidences for potential transition from gastric chief cells in …
Long non-coding RNA CASC2 suppresses pancreatic cancer cell growth and progression by regulating the miR-24/MUC6 axis.
Xu DF, Wang LS, Zhou JH. Xu DF, et al. Int J Oncol. 2020 Feb;56(2):494-507. doi: 10.3892/ijo.2019.4937. Epub 2019 Dec 10. Int J Oncol. 2020. PMID: 31894271 Free PMC article.
In the present study, the expression levels of CASC2, miR-24 and mucin 6 (MUC6) were measured in pancreatic cancer specimens and cell lines by reverse transcription-quantitative PCR. ...Mechanistically, CASC2 sponged miR-24 and activated its downstream target MUC …
In the present study, the expression levels of CASC2, miR-24 and mucin 6 (MUC6) were measured in pancreatic cancer specimens a …
MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.
Betge J, Schneider NI, Harbaum L, Pollheimer MJ, Lindtner RA, Kornprat P, Ebert MP, Langner C. Betge J, et al. Virchows Arch. 2016 Sep;469(3):255-65. doi: 10.1007/s00428-016-1970-5. Virchows Arch. 2016. PMID: 27298226 Free PMC article.
Mucin glycoprotein expression can be altered during the carcinogenic process. The impact on the prognosis of patients with colorectal cancer (CRC) is controversial. We analyzed tumors from 381 patients for MUC1, MUC2, MUC5AC, and MUC6 expression by immunohistochemic …
Mucin glycoprotein expression can be altered during the carcinogenic process. The impact on the prognosis of patients with colorectal can …
Expression of mucins (MUC1, MUC2, MUC5AC and MUC6) in ALK-positive lung cancer: Comparison with EGFR-mutated lung cancer.
Lee HK, Kwon MJ, Seo J, Kim JW, Hong M, Park HR, Min SK, Choe JY, Ra YJ, Jang SH, Hwang YI, Kim HY, Min KW. Lee HK, et al. Pathol Res Pract. 2019 Mar;215(3):459-465. doi: 10.1016/j.prp.2018.12.011. Epub 2018 Dec 10. Pathol Res Pract. 2019. PMID: 30580903 Free article.
We examined the immunohistochemical profiles of mucins MUC1, MUC2, MUC5AC, and MUC6 in 19 ALK + lung cancers compared with 42 EGFR-mutated lung cancers. ...MUC2 and MUC6 expression was not detected in either type of lung cancer. CONCLUSIONS: The …
We examined the immunohistochemical profiles of mucins MUC1, MUC2, MUC5AC, and MUC6 in 19 ALK + lung cancers compared with 42 …
Analysis of MUC6 polymorphisms on the clinicopathologic characteristics of Asian patients with oral squamous cell carcinoma.
Hua CH, Chuang CY, Chien YC, Su CW, Chen SC, Liu LC, Yang SF, Yu YL. Hua CH, et al. J Cell Mol Med. 2023 Sep;27(17):2594-2602. doi: 10.1111/jcmm.17886. Epub 2023 Aug 15. J Cell Mol Med. 2023. PMID: 37581476 Free PMC article.
Many studies have indicated that MUCs play an important role in cancer metastasis. MUC6 expression has been observed in gastric and oncocytic phenotypes and plays an important role during cancer progression. ...Moreover, male oral cancer patients who c …
Many studies have indicated that MUCs play an important role in cancer metastasis. MUC6 expression has been observed in gastri …
MUC6 expression is a preferable prognostic marker for invasive mucinous adenocarcinoma of the lung.
Yamanoi K, Fujii C, Yuzuriha H, Kumazawa M, Shimoda M, Emoto K, Asamura H, Nakayama J. Yamanoi K, et al. Histochem Cell Biol. 2022 Jun;157(6):671-684. doi: 10.1007/s00418-022-02093-1. Epub 2022 Mar 30. Histochem Cell Biol. 2022. PMID: 35353213
Decreased alphaGlcNAc glycosylation on MUC6-positive tumor cells is often observed in premalignant lesions of the stomach, pancreas, and bile duct, and decreased MUC6 expression is seen in invasive cancer of these organs. ...The alphaGlcNAc expression score w …
Decreased alphaGlcNAc glycosylation on MUC6-positive tumor cells is often observed in premalignant lesions of the stomach, pancreas, …
Gastric cancer: basic aspects.
Resende C, Thiel A, Machado JC, Ristimäki A. Resende C, et al. Helicobacter. 2011 Sep;16 Suppl 1:38-44. doi: 10.1111/j.1523-5378.2011.00879.x. Helicobacter. 2011. PMID: 21896084 Review.
Gastric cancer (GC) is a world health burden, ranging as the second cause of cancer death worldwide. ...This review is intended to focus on the recently described basic aspects that play key roles in the process of gastric carcinogenesis. Genetic variants of the gen …
Gastric cancer (GC) is a world health burden, ranging as the second cause of cancer death worldwide. ...This review is intende …
795 results