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Page 1
Muscle Histology Characterization Using H&E Staining and Muscle Fiber Type Classification Using Immunofluorescence Staining.
Wang C, Yue F, Kuang S. Wang C, et al. Bio Protoc. 2017 May 20;7(10):e2279. doi: 10.21769/BioProtoc.2279. Bio Protoc. 2017. PMID: 28752107 Free PMC article.
Muscle fibers in adult skeletal muscles of rodents are classified into 4 subtypes based on the expression of myosin heavy chain proteins: Myh7 (type I fiber), Myh2 (type IIA fiber), Myh1 (type IIX fiber), Myh4 (type IIB fiber). ...
Muscle fibers in adult skeletal muscles of rodents are classified into 4 subtypes based on the expression of myosin heavy chain proteins: My …
Pancreatic Cancer Cell-Conditioned, Human-Derived Primary Myotubes Display Increased Leucine Turnover, Increased Lipid Accumulation, and Reduced Glucose Uptake.
Krapf SA, Lund J, Saqib AUR, Bakke HG, Rustan AC, Thoresen GH, Kase ET. Krapf SA, et al. Metabolites. 2022 Nov 10;12(11):1095. doi: 10.3390/metabo12111095. Metabolites. 2022. PMID: 36355178 Free PMC article.
Metabolic alterations occurring in cancer cells have been seen to also occur in other tissues than cancerous tissue. ...This indicates production and release of substances from pancreatic cancer cells affecting skeletal muscle....
Metabolic alterations occurring in cancer cells have been seen to also occur in other tissues than cancerous tissue. ...This i …
Data mining on identifying diagnosis and prognosis biomarkers in head and neck squamous carcinoma.
Ju G, Yao Z, Zhao Y, Zhao X, Liu F. Ju G, et al. Sci Rep. 2023 Jun 20;13(1):10020. doi: 10.1038/s41598-023-37216-8. Sci Rep. 2023. PMID: 37340028 Free PMC article.
The main DEGs were further analyzed by pan-cancer expression and immune cell infiltration analyses. MYH1, MYH2, and MYH7 were dysregulated in the cancers. Compared with HNSC, their expression levels are lower in the other types of cancers. MYH1, MYH …
The main DEGs were further analyzed by pan-cancer expression and immune cell infiltration analyses. MYH1, MYH2, and MYH7 were …
Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks.
Murach KA, Liu Z, Jude B, Figueiredo VC, Wen Y, Khadgi S, Lim S, Morena da Silva F, Greene NP, Lanner JT, McCarthy JJ, Vechetti IJ, von Walden F. Murach KA, et al. J Biol Chem. 2022 Nov;298(11):102515. doi: 10.1016/j.jbc.2022.102515. Epub 2022 Sep 21. J Biol Chem. 2022. PMID: 36150502 Free PMC article.
Myc is a powerful transcription factor implicated in epigenetic reprogramming, cellular plasticity, and rapid growth as well as tumorigenesis. Cancer in skeletal muscle is extremely rare despite marked and sustained Myc induction during loading-induced hypertrophy. ...Spec …
Myc is a powerful transcription factor implicated in epigenetic reprogramming, cellular plasticity, and rapid growth as well as tumorigenesi …
Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy.
Kim HJ, Lee JH, Kim SW, Lee SH, Jung DW, Williams DR. Kim HJ, et al. PLoS One. 2021 May 26;16(5):e0252135. doi: 10.1371/journal.pone.0252135. eCollection 2021. PLoS One. 2021. PMID: 34038481 Free PMC article.
Muscle atrophy is also feature of cancer cachexia. IC50 analyses indicated that niclosamide was more cytotoxic for myoblasts than cancer cells. In addition, niclosamide did not suppress the induction of iNOS, a key mediator of atrophy, in an in vitro model of can …
Muscle atrophy is also feature of cancer cachexia. IC50 analyses indicated that niclosamide was more cytotoxic for myoblasts than …
Analysis of myosin genes in HNSCC and identify MYL1 as a specific poor prognostic biomarker, promotes tumor metastasis and correlates with tumor immune infiltration in HNSCC.
Li C, Guan R, Li W, Wei D, Cao S, Chang F, Wei Q, Wei R, Chen L, Xu C, Wu K, Lei D. Li C, et al. BMC Cancer. 2023 Sep 7;23(1):840. doi: 10.1186/s12885-023-11349-5. BMC Cancer. 2023. PMID: 37679666 Free PMC article.
The results showed that MYL1, MYL2, MYL3, MYH2, and MYH7 were down-regulated, while MYH10 was up-regulated in patients with HNSCC. Interestingly, MYL1, MYL2, MYH1, MYH2, and MYH7 were shown to be unfavorable prognostic markers in HNSCC. ...
The results showed that MYL1, MYL2, MYL3, MYH2, and MYH7 were down-regulated, while MYH10 was up-regulated in patients with HNSCC. In …
Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics.
Gong B, Kao Y, Zhang C, Sun F, Gong Z, Chen J. Gong B, et al. Mediators Inflamm. 2020 Apr 9;2020:5934821. doi: 10.1155/2020/5934821. eCollection 2020. Mediators Inflamm. 2020. PMID: 32351322 Free PMC article.
The high mortality of colorectal cancer (CRC) patients and the limitations of conventional tumor-node-metastasis (TNM) stage emphasized the necessity of exploring hub genes closely related to carcinogenesis and prognosis in CRC. ...We identified and validated 212 different …
The high mortality of colorectal cancer (CRC) patients and the limitations of conventional tumor-node-metastasis (TNM) stage emphasiz …
Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers.
Zheng CX, Gu ZH, Han B, Zhang RX, Pan CM, Xiang Y, Rong XJ, Chen X, Li QY, Wan HY. Zheng CX, et al. Int J Oncol. 2013 Sep;43(3):755-64. doi: 10.3892/ijo.2013.1991. Epub 2013 Jun 25. Int J Oncol. 2013. PMID: 23799614
Squamous cell lung cancer is a major histotype of non-small cell lung cancer (NSCLC) that is distinct from lung adenocarcinoma. ...Taken together, our results implicate TP53, EP300, LPHN2, C10orf137, MYH2, TGM2 and MS4A3 as potential driver genes of squamous …
Squamous cell lung cancer is a major histotype of non-small cell lung cancer (NSCLC) that is distinct from lung adenocarcinoma …
Skeletal Muscle Proteomic Profile Revealed Gender-Related Metabolic Responses in a Diet-Induced Obesity Animal Model.
Moriggi M, Belloli S, Barbacini P, Murtaj V, Torretta E, Chaabane L, Canu T, Penati S, Malosio ML, Esposito A, Gelfi C, Moresco RM, Capitanio D. Moriggi M, et al. Int J Mol Sci. 2021 Apr 28;22(9):4680. doi: 10.3390/ijms22094680. Int J Mol Sci. 2021. PMID: 33925229 Free PMC article.
Obesity is a chronic, complex pathology associated with a risk of developing secondary pathologies, including cardiovascular diseases, cancer, type 2 diabetes (T2DM) and musculoskeletal disorders. Since skeletal muscle accounts for more than 70% of total glucose disposal, …
Obesity is a chronic, complex pathology associated with a risk of developing secondary pathologies, including cardiovascular diseases, ca …
Platinum-based anticancer drugs-induced downregulation of myosin heavy chain isoforms in skeletal muscle of mouse.
Sato K, Miyauchi Y, Xu X, Kon R, Ikarashi N, Chiba Y, Hosoe T, Sakai H. Sato K, et al. J Pharmacol Sci. 2023 Jul;152(3):167-177. doi: 10.1016/j.jphs.2023.04.009. Epub 2023 Apr 29. J Pharmacol Sci. 2023. PMID: 37257944 Free article.
Cisplatin, a platinum-based anticancer drug used frequently in cancer treatment, causes skeletal muscle atrophy. It was predicted that the proteolytic pathway is enhanced as the mechanism of this atrophy. ...The expression of Mef2c, which was predicted to act upstream of …
Cisplatin, a platinum-based anticancer drug used frequently in cancer treatment, causes skeletal muscle atrophy. It was predicted tha …
20 results